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NCT05219838 · ClinicalTrials.gov registry record · Phase 1

Binding and Effects of Lu AG06466 in the Brain of Healthy Men

A Phase 1 study, sponsored by H. Lundbeck A/S.

Completed
Registry status
Phase 1
Development phase
8
Enrollment target

NCT05219838 is a Phase 1 study that has completed, run by H. Lundbeck A/S. The registered enrollment target is 8 participants.

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The verdict

NCT05219838, a Phase 1 study, has completed, sponsored by H. Lundbeck A/S.

COMPLETED
Registry status
Phase 1
Development phase
8 participants
Enrollment target

Study Summary

This study is being done to learn about the binding of Lu AG06466 and its major breakdown product (Lu AG06988) in the brain of healthy men having received multiple doses of Lu AG06466. As the binding will result in inhibition of an enzyme in the endocannabinoid system called monoacylglycerol lipase (MAGL), the effects on this system will be evaluated both in the blood and cerebrospinal fluid and compared to the binding in the brain.

Interventions

  • DRUG Lu AG06466

Trial Details

FieldValue
Enrollment Target 8 participants
Start Date 2022-01-18
Est. Completion 2022-08-29
Phase Phase 1

Sponsor

H. Lundbeck A/S

72 total trials

What the Registry Record Tells You About NCT05219838

The ClinicalTrials.gov registry entry for NCT05219838 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 8 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is H. Lundbeck A/S, which has 72 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Lu AG06466 is the first listed.

NCT05219838 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05219838 about?

NCT05219838 is a clinical study titled "Binding and Effects of Lu AG06466 in the Brain of Healthy Men". This study is being done to learn about the binding of Lu AG06466 and its major breakdown product (Lu AG06988) in the brain of healthy men having received multiple doses of Lu AG06466. As the binding will result in inhibition of an enzyme in the endocannabinoid system called monoacylglycerol lipase ...

What is the current status of trial NCT05219838?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2022-01-18. Estimated completion is 2022-08-29.

What interventions are being tested in trial NCT05219838?

The interventions under investigation include: Lu AG06466 (DRUG).

Who is sponsoring clinical trial NCT05219838?

This trial is sponsored by H. Lundbeck A/S, which has 72 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.