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NCT05209867 · ClinicalTrials.gov registry record · Phase 4
Single-cell CBD Biomarkers of Inflammation Reduction in People Living With HIV
A Phase 4 study, sponsored by University of Florida.
- Completed
- Registry status
- Phase 4
- Development phase
- 4
- Enrollment target
NCT05209867: Completed Phase 4 study, sponsored by University of Florida.
NCT05209867 is a Phase 4 study that has completed, run by University of Florida. The registered enrollment target is 4 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05209867, a Phase 4 study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 4 participants
- Enrollment target
Study Summary
People living with HIV (PLWH) are affected by comorbidities appearing to be strongly related to chronic inflammation, a condition characterizing PLWH. The investigators propose to study the effects of CBD on inflammation in PLWH, and establish the molecular role of different immune cells in this process. The investigators plan to use single cell RNA-sequencing (scRNAseq) to isolate CBD-specific cellular phenotypes from five persons with HIV who will provide blood samples before and after taking CBD.
Primary Outcome
Number of genes with a significant fold change before/after CBD in PBMCs (Peripheral Blood Mononuclear Cells) related to inflammation genes, calculated before and after CBD treatment (baseline and 1 month for 1 participant, 2 months for 2 participants).
Interventions
- DRUG CBD oil
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2022-05-01 |
| Est. Completion | 2022-12-12 |
| Phase | Phase 4 |
What the finished NCT05209867 record still lists
NCT05209867 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which CBD oil is the first listed.
NCT05209867 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05209867 about?
NCT05209867 is a clinical study titled "Single-cell CBD Biomarkers of Inflammation Reduction in People Living With HIV". People living with HIV (PLWH) are affected by comorbidities appearing to be strongly related to chronic inflammation, a condition characterizing PLWH. The investigators propose to study the effects of CBD on inflammation in PLWH, and establish the molecular role of different immune cells in this pr...
What is the current status of trial NCT05209867?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 4 participants. The study started on 2022-05-01. Estimated completion is 2022-12-12.
What interventions are being tested in trial NCT05209867?
The interventions under investigation include: CBD oil (DRUG).
Who is sponsoring clinical trial NCT05209867?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05209867's enrollment target sits among peer trials
4 1994th of 2000 higher than 6 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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