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NCT05203861 · ClinicalTrials.gov registry record · NA
Affect Treatment for Depression and Anxiety
A NA study, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- NA
- Development phase
- 100
- Enrollment target
NCT05203861: Completed NA study, sponsored by University of California, Los Angeles.
NCT05203861 is a NA study that has completed, run by University of California, Los Angeles. The registered enrollment target is 100 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05203861, a NA study, has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the efficacy and mediators of change in Positive Affect Treatment, a psychotherapy specifically aimed at enhancing reward sensitivity in individuals with low positive affect (a core feature of anhedonia) in the context of depression or anxiety. Target enrollment is 100 male and female participants with low positive affect and depression or anxiety and impaired functioning, between the ages of 18 and 65 years, who will be randomized to either Positive Affect Treatment or Negative Affect Treatment (designed to reduce threat sensitivity). Participants will complete laboratory tests, psychiatric assessments, and self-report questionnaires as part of the study. The total length of participation is around 5 months.
Primary Outcome
Reported positive affect (general dimensions scale positive affect) and negative affect (general dimension scale negative affect) (score range for each scale: 10-50, higher scores represent higher levels of positive affect or negative affect).
Interventions
- BEHAVIORAL Positive Affect Treatment
- BEHAVIORAL Negative Affect Treatment
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2021-11-22 |
| Est. Completion | 2024-05-31 |
| Phase | NA |
What the finished NCT05203861 record still lists
NCT05203861 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 2 interventions - of which Positive Affect Treatment is the first listed.
NCT05203861 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05203861 about?
NCT05203861 is a clinical study titled "Affect Treatment for Depression and Anxiety". The purpose of this study is to evaluate the efficacy and mediators of change in Positive Affect Treatment, a psychotherapy specifically aimed at enhancing reward sensitivity in individuals with low positive affect (a core feature of anhedonia) in the context of depression or anxiety. Target enroll...
What is the current status of trial NCT05203861?
This trial is currently completed. It is a NA study. The enrollment target is 100 participants. The study started on 2021-11-22. Estimated completion is 2024-05-31.
What interventions are being tested in trial NCT05203861?
The interventions under investigation include: Positive Affect Treatment (BEHAVIORAL), Negative Affect Treatment (BEHAVIORAL).
Who is sponsoring clinical trial NCT05203861?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05203861's enrollment target sits among peer trials
100 840th of 2000 higher than 1,081 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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