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NCT05200364 · ClinicalTrials.gov registry record · Phase 1

A Study of STRO-002, an Anti-Folate Receptor Alpha Antibody Drug Conjugate, in Combination With Bevacizumab in Epithelial Ovarian Cancer

A Phase 1 study, sponsored by Sutro Biopharma.

Terminated
Registry status
Phase 1
Development phase
58
Enrollment target

NCT05200364: Clinical Trial Phase 1 study, sponsored by Sutro Biopharma.

NCT05200364 is a Phase 1 study that was terminated before completion, run by Sutro Biopharma. The registered enrollment target is 58 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05200364, a Phase 1 study, was terminated before completion, sponsored by Sutro Biopharma.

TERMINATED
Registry status
Phase 1
Development phase
58 participants
Enrollment target

Study Summary

Phase 1 trial to study the safety, pharmacokinetic and Preliminary Efficacy of STRO-002 in combination with Bevacizumab.

Primary Outcome

Incidence and severity of adverse events (AEs) and clinical laboratory abnormalities observed across STRO-002/bevacizumab dose levels. Incidence of dose-limiting toxicities (DLTs) through Day 1-21 following administration of each initial STRO-002/bevacizumab dose.

Interventions

  • DRUG Bevacizumab
  • DRUG STRO-002

Trial Details

FieldValue
Enrollment Target 58 participants
Start Date 2022-03-22
Est. Completion 2025-06-01
Phase Phase 1
Sutro Biopharma

6 total trials

Why NCT05200364 stopped before completion

NCT05200364 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 58 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.

The record links to 0 conditions, and to 2 interventions - of which Bevacizumab is the first listed.

NCT05200364 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05200364 about?

NCT05200364 is a clinical study titled "A Study of STRO-002, an Anti-Folate Receptor Alpha Antibody Drug Conjugate, in Combination With Bevacizumab in Epithelial Ovarian Cancer". Phase 1 trial to study the safety, pharmacokinetic and Preliminary Efficacy of STRO-002 in combination with Bevacizumab.

What is the current status of trial NCT05200364?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 58 participants. The study started on 2022-03-22. Estimated completion is 2025-06-01.

What interventions are being tested in trial NCT05200364?

The interventions under investigation include: Bevacizumab (DRUG), STRO-002 (DRUG).

Who is sponsoring clinical trial NCT05200364?

This trial is sponsored by Sutro Biopharma, which has 6 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05200364's enrollment target sits among peer trials

58 895th of 2000 higher than 1,100 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05200364, the US trial registry maintained by the National Library of Medicine. NCT05200364 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.