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NCT05199597 · ClinicalTrials.gov registry record · Early Phase 1
The Response to Atropine Drops (RAD) Study
A Early Phase 1 study, sponsored by Ohio State University.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 30
- Enrollment target
NCT05199597: Completed Early Phase 1 study, sponsored by Ohio State University.
NCT05199597 is a Early Phase 1 study that has completed, run by Ohio State University. The registered enrollment target is 30 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (43% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05199597, a Early Phase 1 study, has completed, sponsored by Ohio State University.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 30 participants
- Enrollment target
Study Summary
The purpose of this study is to examine the comfort of giving low concentration atropine eye drops.
Primary Outcome
We will compare the amount of time that it takes a participant to report that the eye comfort is "0," meaning that it returned to baseline comfort, for the following drop comparisons: 1. 0.01% at room temperature from Lab A and 0.05% at room temperature from Lab A (comparing concentrations) 2. 0.05% at room temperature from Lab A and 0.05% refrigerated from Lab A (comparing temperatures) 3. 0.05% at room temperature from Lab A and 0.05% at room temperature from Lab B (comparing labs)
Interventions
- DRUG 0.01% atropine
- DRUG 0.05% atropine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2022-05-19 |
| Est. Completion | 2022-06-15 |
| Phase | Early Phase 1 |
What the finished NCT05199597 record still lists
NCT05199597 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (43% lower).
The record links to 0 conditions, and to 2 interventions - of which 0.01% atropine is the first listed.
NCT05199597 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05199597 about?
NCT05199597 is a clinical study titled "The Response to Atropine Drops (RAD) Study". The purpose of this study is to examine the comfort of giving low concentration atropine eye drops.
What is the current status of trial NCT05199597?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 30 participants. The study started on 2022-05-19. Estimated completion is 2022-06-15.
What interventions are being tested in trial NCT05199597?
The interventions under investigation include: 0.01% atropine (DRUG), 0.05% atropine (DRUG).
Who is sponsoring clinical trial NCT05199597?
This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05199597's enrollment target sits among peer trials
30 807th of 2000 higher than 1,075 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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