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NCT05194358 · ClinicalTrials.gov registry record · Phase 1
Study of SIAN Nasal Spray in Healthy Adults
A Phase 1 study, sponsored by Emergent BioSolutions.
- Completed
- Registry status
- Phase 1
- Development phase
- 47
- Enrollment target
NCT05194358: Completed Phase 1 study, sponsored by Emergent BioSolutions.
NCT05194358 is a Phase 1 study that has completed, run by Emergent BioSolutions. The registered enrollment target is 47 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (22% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05194358, a Phase 1 study, has completed, sponsored by Emergent BioSolutions.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 47 participants
- Enrollment target
Study Summary
This study is designed to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending doses of Stabilized Isoamyl Nitrite (SIAN) nasal spray in healthy subjects.
Primary Outcome
Incidence of related SAEs
Interventions
- DRUG Stabilized Isoamyl Nitrite (SIAN)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 47 participants |
| Start Date | 2021-12-21 |
| Est. Completion | 2023-10-13 |
| Phase | Phase 1 |
What the finished NCT05194358 record still lists
NCT05194358 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 47 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (22% lower).
The record links to 0 conditions, and to 1 intervention - of which Stabilized Isoamyl Nitrite (SIAN) is the first listed.
NCT05194358 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05194358 about?
NCT05194358 is a clinical study titled "Study of SIAN Nasal Spray in Healthy Adults". This study is designed to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending doses of Stabilized Isoamyl Nitrite (SIAN) nasal spray in healthy subjects.
What is the current status of trial NCT05194358?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 47 participants. The study started on 2021-12-21. Estimated completion is 2023-10-13.
What interventions are being tested in trial NCT05194358?
The interventions under investigation include: Stabilized Isoamyl Nitrite (SIAN) (DRUG).
Who is sponsoring clinical trial NCT05194358?
This trial is sponsored by Emergent BioSolutions, which has 34 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05194358's enrollment target sits among peer trials
47 1053rd of 2000 higher than 943 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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