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NCT05192369 · ClinicalTrials.gov registry record · Phase 1
A Randomized Study to Evaluate the Effects of CTP-543 on the QT/QTc Intervals in Health Volunteers
A Phase 1 study, sponsored by Concert Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
NCT05192369: Completed Phase 1 study, sponsored by Concert Pharmaceuticals.
NCT05192369 is a Phase 1 study that has completed, run by Concert Pharmaceuticals. The registered enrollment target is 48 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05192369, a Phase 1 study, has completed, sponsored by Concert Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
Study Summary
This is a four-arm, randomized, crossover, placebo and active controlled study to evaluate of the effect of therapeutic and supratherapeutic doses of CTP-543 on the QT/QTc intervals in healthy volunteers
Primary Outcome
Analysis of the change from pre-dose-averaged baseline Fridericia's corrected QT interval (QTcF) at each post-dose timepoint
Interventions
- DRUG Placebo
- DRUG Moxifloxacin
- DRUG CTP-543
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2022-01-04 |
| Est. Completion | 2022-01-28 |
| Phase | Phase 1 |
What the finished NCT05192369 record still lists
NCT05192369 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT05192369 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05192369 about?
NCT05192369 is a clinical study titled "A Randomized Study to Evaluate the Effects of CTP-543 on the QT/QTc Intervals in Health Volunteers". This is a four-arm, randomized, crossover, placebo and active controlled study to evaluate of the effect of therapeutic and supratherapeutic doses of CTP-543 on the QT/QTc intervals in healthy volunteers
What is the current status of trial NCT05192369?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2022-01-04. Estimated completion is 2022-01-28.
What interventions are being tested in trial NCT05192369?
The interventions under investigation include: Placebo (DRUG), Moxifloxacin (DRUG), CTP-543 (DRUG).
Who is sponsoring clinical trial NCT05192369?
This trial is sponsored by Concert Pharmaceuticals, which has 24 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05192369's enrollment target sits among peer trials
48 1025th of 2000 higher than 948 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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