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NCT05182476 · ClinicalTrials.gov registry record · Phase 2
Study to Evaluate the Efficacy, Safety, and Tolerability of Luvadaxistat in Participants With Cognitive Impairment Associated With Schizophrenia
A Phase 2 study, sponsored by Neurocrine Biosciences.
- Terminated
- Registry status
- Phase 2
- Development phase
- 216
- Enrollment target
NCT05182476: Clinical Trial Phase 2 study, sponsored by Neurocrine Biosciences.
NCT05182476 is a Phase 2 study that was terminated before completion, run by Neurocrine Biosciences. The registered enrollment target is 216 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05182476, a Phase 2 study, was terminated before completion, sponsored by Neurocrine Biosciences.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 216 participants
- Enrollment target
Study Summary
Study to evaluate the safety and efficacy of luvadaxistat compared with placebo on improving cognitive performance in participants with schizophrenia.
Interventions
- DRUG Placebo
- DRUG Luvadaxistat
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 216 participants |
| Start Date | 2021-12-07 |
| Est. Completion | 2024-10-14 |
| Phase | Phase 2 |
Why NCT05182476 stopped before completion
NCT05182476 is an interventional study that assigns participants to a tested intervention. The registered 216 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05182476 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05182476 about?
NCT05182476 is a clinical study titled "Study to Evaluate the Efficacy, Safety, and Tolerability of Luvadaxistat in Participants With Cognitive Impairment Associated With Schizophrenia". Study to evaluate the safety and efficacy of luvadaxistat compared with placebo on improving cognitive performance in participants with schizophrenia.
What is the current status of trial NCT05182476?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 216 participants. The study started on 2021-12-07. Estimated completion is 2024-10-14.
What interventions are being tested in trial NCT05182476?
The interventions under investigation include: Placebo (DRUG), Luvadaxistat (DRUG).
Who is sponsoring clinical trial NCT05182476?
This trial is sponsored by Neurocrine Biosciences, which has 65 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05182476's enrollment target sits among peer trials
216 286th of 2000 higher than 1,712 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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