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NCT05178784 · ClinicalTrials.gov registry record
EEG Biomarker Study for Participants in the Neurolief "MOOD" Trial
A clinical trial of Depression, sponsored by Butler Hospital.
- Active
- Registry status
- 40
- Enrollment target
- 1
- Study location
NCT05178784: Active study of Depression, sponsored by Butler Hospital.
NCT05178784 is a study of Depression that is active but no longer recruiting, run by Butler Hospital. The registered enrollment target is 40 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05178784, a study of Depression, is active but no longer recruiting, sponsored by Butler Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will collect EEG data at 3 time points from up to 40 adults who are enrolled in a double clinical trial investigating a device that delivers noninvasive, self-administered external Combined Occipital and Trigeminal Neurostimulation (eCOT-NS) treatment for Major Depressive Disorder (Relivion®DP). Baseline (Pre-treatment) Frontal EEG Alpha Oscillations (Power) will be compared post-stimulation power.
Primary Outcome
Change from Pre- to Post- Stimulation Power in Frontal Electrodes at Individual Alpha Frequency Peak (IAF), as recorded in resting state EEG. Calulated as (post-pre)/ (pre+post)
Conditions Studied
Interventions
- DEVICE External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) stimulation
Study Locations (1)
Rhode Island
- Butler Hospital - Providence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2021-11-16 |
| Est. Completion | 2025-11-16 |
What the registry record for NCT05178784 still lists
NCT05178784 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 1 intervention - of which External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) stimulation is the first listed.
NCT05178784 reports a single indexed study location in Rhode Island.
Frequently Asked Questions
What is clinical trial NCT05178784 about?
NCT05178784 is a clinical study titled "EEG Biomarker Study for Participants in the Neurolief "MOOD" Trial". This study will collect EEG data at 3 time points from up to 40 adults who are enrolled in a double clinical trial investigating a device that delivers noninvasive, self-administered external Combined Occipital and Trigeminal Neurostimulation (eCOT-NS) treatment for Major Depressive Disorder (Relivi...
What is the current status of trial NCT05178784?
This trial is currently active not recruiting. The enrollment target is 40 participants. The study started on 2021-11-16. Estimated completion is 2025-11-16.
What conditions does trial NCT05178784 study?
This clinical trial studies the following conditions: Depression.
What interventions are being tested in trial NCT05178784?
The interventions under investigation include: External Combined Occipital and Trigeminal Nerve Stimulation (eCOT-NS) stimulation (DEVICE).
Who is sponsoring clinical trial NCT05178784?
This trial is sponsored by Butler Hospital, which has 103 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05178784 being conducted?
This trial has 1 study location across Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05178784's enrollment target sits among peer trials
40 509th of 679 higher than 151 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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