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NCT05177991 · ClinicalTrials.gov registry record · Early Phase 1

Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs

A Early Phase 1 study of Ventral Hernia and Inguinal Hernia, sponsored by Leslie Son.

Active
Registry status
Early Phase 1
Development phase
200
Enrollment target
1
Study location

NCT05177991 is a Early Phase 1 study of Ventral Hernia and Inguinal Hernia that is active but no longer recruiting, run by Leslie Son. The registered enrollment target is 200 participants, above the 132-participant average among 18 other Ventral Hernia trials with a reported enrollment target (52% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT05177991, a Early Phase 1 study of Ventral Hernia and Inguinal Hernia, is active but no longer recruiting, sponsored by Leslie Son.

ACTIVE NOT RECRUITING
Registry status
Early Phase 1
Development phase
200 participants
Enrollment target
1
Study location

Study Summary

While studies have shown improved postoperative pain control with TAP blocks after inguinal and ventral hernia repair, data comparing Liposomal bupivacaine (Exparel) to bupivacaine alone in formulation of the TAP block is particularly scarce. Therefore, we designed a prospective, randomized trial comparing the postoperative pain control in minimally invasive ventral and inguinal hernia repair patients who receive an Exaparel-based TAP block compared to the traditional bupivacaine (Marcaine) TAP block.

Interventions

  • DRUG Bupivacaine
  • DRUG Liposomal Bupivacaine

Study Locations (1)

Louisiana

  • Karl LeBlanc - Baton Rouge

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2022-03-01
Est. Completion 2025-12-31
Phase Early Phase 1

Sponsor

Leslie Son

1 total trials

What the Registry Record Tells You About NCT05177991

The ClinicalTrials.gov registry entry for NCT05177991 describes a study currently listed as active not recruiting, categorized as Early Phase 1. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 132-participant average among 18 other Ventral Hernia trials with a reported enrollment target (52% higher). The listed sponsor is Leslie Son, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Ventral Hernia appearing as the primary indexed condition, and to 2 interventions - of which Bupivacaine is the first listed.

NCT05177991 reports 1 study location spanning 1 distinct geographic area - top geographies include Louisiana.

Frequently Asked Questions

What is clinical trial NCT05177991 about?

NCT05177991 is a clinical study titled "Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs". While studies have shown improved postoperative pain control with TAP blocks after inguinal and ventral hernia repair, data comparing Liposomal bupivacaine (Exparel) to bupivacaine alone in formulation of the TAP block is particularly scarce. Therefore, we designed a prospective, randomized trial co...

What is the current status of trial NCT05177991?

This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 200 participants. The study started on 2022-03-01. Estimated completion is 2025-12-31.

What conditions does trial NCT05177991 study?

This clinical trial studies the following conditions: Ventral Hernia, Inguinal Hernia.

What interventions are being tested in trial NCT05177991?

The interventions under investigation include: Bupivacaine (DRUG), Liposomal Bupivacaine (DRUG).

Who is sponsoring clinical trial NCT05177991?

This trial is sponsored by Leslie Son, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05177991 being conducted?

This trial has 1 study location across Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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