Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05171881 · ClinicalTrials.gov registry record · Phase 2
Brain Oxygenation-II
A Phase 2 study of Cerebral Hypoxia, sponsored by Valerie Chock, M.D., M.S. Epi.
- Active
- Registry status
- Phase 2
- Development phase
- 100
- Enrollment target
- 5
- Study locations
NCT05171881: Active Phase 2 study of Cerebral Hypoxia, sponsored by Valerie Chock, M.D., M.S. Epi.
NCT05171881 is a Phase 2 study of Cerebral Hypoxia that is active but no longer recruiting, run by Valerie Chock, M.D., M.S. Epi. The registered enrollment target is 100 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower). The trial reports 5 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05171881, a Phase 2 study of Cerebral Hypoxia, is active but no longer recruiting, sponsored by Valerie Chock, M.D., M.S. Epi.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 100 participants
- Enrollment target
- 5
- Study locations
Study Summary
The Brain Oxygenation-II study (BOx-II) is a phase-II, multicenter, single-arm clinical trial evaluating interventions based on near-infrared spectroscopy (NIRS) monitoring of cerebral oxygen saturation in extremely premature infants. Enrolled infants will follow a treatment guideline to maintain cerebral oxygen saturation in a target range within the first 72 hours of life. The primary outcomes will include interventions used to maintain cerebral saturation in target range, rates of cerebral hypoxia and systemic hypoxia, and a composite of death or severe brain injury detected on term-equivalent magnetic resonance imaging.
Conditions Studied
Interventions
- OTHER Intervention for cerebral hypoxia
Study Locations (5)
California
- Loma Linda University - Loma Linda
- Stanford University - Palo Alto
Missouri
- Washington University in Saint Louis - St Louis
Texas
- University of Texas- Southwestern Medical Center - Dallas
Virginia
- University of Virginia - Charlottesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2022-04-07 |
| Est. Completion | 2025-04 |
| Phase | Phase 2 |
What the registry record for NCT05171881 still lists
NCT05171881 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower).
The record links to 1 condition, with Cerebral Hypoxia appearing as the primary indexed condition, and to 1 intervention - of which Intervention for cerebral hypoxia is the first listed.
NCT05171881 lists 5 locations in 4 states (California, Missouri, Texas).
Frequently Asked Questions
What is clinical trial NCT05171881 about?
NCT05171881 is a clinical study titled "Brain Oxygenation-II". The Brain Oxygenation-II study (BOx-II) is a phase-II, multicenter, single-arm clinical trial evaluating interventions based on near-infrared spectroscopy (NIRS) monitoring of cerebral oxygen saturation in extremely premature infants. Enrolled infants will follow a treatment guideline to maintain ce...
What is the current status of trial NCT05171881?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2022-04-07. Estimated completion is 2025-04.
What conditions does trial NCT05171881 study?
This clinical trial studies the following conditions: Cerebral Hypoxia.
What interventions are being tested in trial NCT05171881?
The interventions under investigation include: Intervention for cerebral hypoxia (OTHER).
Who is sponsoring clinical trial NCT05171881?
This trial is sponsored by Valerie Chock, M.D., M.S. Epi, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05171881 being conducted?
This trial has 5 study locations across California, Missouri, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cerebral Hypoxia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05171881's enrollment target sits among peer trials
100 672nd of 2000 higher than 1,263 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01048281 · 100 participants
Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
- NCT01161199 · 100 participants
The Use of Leukapheresis to Support HIV Pathogenesis Studies
- NCT01327690 · 100 participants · Early Phase 1
Mental Health in Veterans and Families After Group Therapies
- NCT01730781 · 100 participants
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI