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NCT05163899 · ClinicalTrials.gov registry record · Phase 2
Investigation of Surgical Sectioning of the Filum Terminale in Treating Occult Tethered Cord Syndrome Patients
A Phase 2 study of Tethered Cord and Tethered Cord Syndrome, sponsored by Weill Medical College of Cornell University.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05163899: Recruiting Phase 2 study of Tethered Cord and Tethered Cord Syndrome, sponsored by Weill Medical College of Cornell University.
NCT05163899 is a Phase 2 study of Tethered Cord and Tethered Cord Syndrome that is actively recruiting participants, run by Weill Medical College of Cornell University. The registered enrollment target is 20 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05163899, a Phase 2 study of Tethered Cord and Tethered Cord Syndrome, is actively recruiting participants, sponsored by Weill Medical College of Cornell University.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators hypothesize that surgical release of the filum terminale (strand of fibrous tissue at the end of the spinal cord) is a more efficacious treatment option for symptomatic relief than medical management in subjects with Occult Tethered Cord Syndrome (OTCS) and that the risks do not outweigh the benefit profile.
Primary Outcome
Combination of neurologic, urologic, orthopedic, and cutaneous assessments. The OCCULT Scale is from 0-100, with 0 being none of the listed signs/symptoms present and 100 being all listed signs/symptoms present with maximum severity.
Conditions Studied
Interventions
- PROCEDURE Release of filum terminale
Study Locations (1)
New York
- Weill Cornell Medicine - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2022-05-19 |
| Est. Completion | 2028-05 |
| Phase | Phase 2 |
What NCT05163899 shows while recruiting
NCT05163899 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower).
The record links to 4 conditions, with Tethered Cord appearing as the primary indexed condition, and to 1 intervention - of which Release of filum terminale is the first listed.
NCT05163899 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT05163899 about?
NCT05163899 is a clinical study titled "Investigation of Surgical Sectioning of the Filum Terminale in Treating Occult Tethered Cord Syndrome Patients". The investigators hypothesize that surgical release of the filum terminale (strand of fibrous tissue at the end of the spinal cord) is a more efficacious treatment option for symptomatic relief than medical management in subjects with Occult Tethered Cord Syndrome (OTCS) and that the risks do not ou...
What is the current status of trial NCT05163899?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2022-05-19. Estimated completion is 2028-05.
What conditions does trial NCT05163899 study?
This clinical trial studies the following conditions: Tethered Cord, Tethered Cord Syndrome, Occult Spina Bifida, Spina Bifida Occulta.
What interventions are being tested in trial NCT05163899?
The interventions under investigation include: Release of filum terminale (PROCEDURE).
Who is sponsoring clinical trial NCT05163899?
This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05163899 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05163899's enrollment target sits among peer trials
20 1805th of 2000 higher than 107 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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