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NCT05156398 · ClinicalTrials.gov registry record · Phase 3
Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects
A Phase 3 study of Migraine, sponsored by Pfizer.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 640
- Enrollment target
- 20
- Study locations
NCT05156398: Recruiting Phase 3 study of Migraine, sponsored by Pfizer.
NCT05156398 is a Phase 3 study of Migraine that is actively recruiting participants, run by Pfizer. The registered enrollment target is 640 participants, above the 352-participant average among 102 other Migraine trials with a reported enrollment target (82% higher). The trial reports 20 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05156398, a Phase 3 study of Migraine, is actively recruiting participants, sponsored by Pfizer.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 640 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to compare the efficacy and safety of rimegepant to placebo as a preventative treatment for migraine in children and adolescents ≥ 6 to \<18 years with episodic migraine.
Primary Outcome
Reduction from baseline in mean number of migraine days per month
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Rimegepant
Study Locations (20)
Florida
- Accel Research Sites Network - Edgewater Clinical Research Unit - Edgewater
- Direct Helpers Research Center - Hialeah
- New Med Research, Inc - Hollywood
- Complete Health Research - Ormond Beach
- D&H Tamarac Research Center LLC - Tamarac
- Santos Research Center, CORP - Tampa
Georgia
- Augusta University - Augusta
- WR-Mount Vernon Clinical Research, LLC - Sandy Springs
- Meridian Clinical Research, LLC - Savannah
- Extraordinary Family Healthcare - Snellville
- Renew Health Clinical Research LLC - Snellville
California
- Advanced Investigative Medicine, Inc. - Hawthorne
- Velocity Clinical Research San Diego - La Mesa
Colorado
- Colorado Springs Neurological Associates - Colorado Springs
- Advanced Neurosciences Research, LLC - Fort Collins
Arkansas
- The Belinga Clinic - Fort Smith
District of Columbia
- Meridian Clinical Research, LLC - Washington D.C.
Idaho
- Northwest Clinical Trials, Inc. - Boise
Illinois
- Diamond Headache Clinic - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 640 participants |
| Start Date | 2022-02-28 |
| Est. Completion | 2032-11-27 |
| Phase | Phase 3 |
What NCT05156398 shows while recruiting
NCT05156398 is an interventional study that assigns participants to a tested intervention. The registered 640 participants enrollment target is mid-sized for trials with a published cap, above the 352-participant average among 102 other Migraine trials with a reported enrollment target (82% higher).
The record links to 1 condition, with Migraine appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT05156398 names 20 study sites across 9 states, led by Florida, Georgia, California.
Frequently Asked Questions
What is clinical trial NCT05156398 about?
NCT05156398 is a clinical study titled "Efficacy and Safety Study of Rimegepant for the Preventative Treatment of Migraine in Pediatric Subjects". The purpose of this study is to compare the efficacy and safety of rimegepant to placebo as a preventative treatment for migraine in children and adolescents ≥ 6 to \<18 years with episodic migraine.
What is the current status of trial NCT05156398?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 640 participants. The study started on 2022-02-28. Estimated completion is 2032-11-27.
What conditions does trial NCT05156398 study?
This clinical trial studies the following conditions: Migraine.
What interventions are being tested in trial NCT05156398?
The interventions under investigation include: Placebo (DRUG), Rimegepant (DRUG).
Who is sponsoring clinical trial NCT05156398?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05156398 being conducted?
This trial has 20 study locations across Arkansas, California, Colorado, District of Columbia, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Migraine
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05156398's enrollment target sits among peer trials
640 15th of 102 higher than 88 of 102 other Migraine trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Migraine trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines
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