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NCT05153330 · ClinicalTrials.gov registry record · Phase 1

Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLL

A Phase 1 study, sponsored by Biomea Fusion.

Terminated
Registry status
Phase 1
Development phase
55
Enrollment target

NCT05153330 is a Phase 1 study that was terminated before completion, run by Biomea Fusion. The registered enrollment target is 55 participants.

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The verdict

NCT05153330, a Phase 1 study, was terminated before completion, sponsored by Biomea Fusion.

TERMINATED
Registry status
Phase 1
Development phase
55 participants
Enrollment target

Study Summary

A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-219, an oral covalent menin inhibitor, in adult patients with AML, ALL (with KMT2A/ MLL1r, NPM1 mutations), DLBCL, MM, and CLL/SLL.

Interventions

  • DRUG BMF-219

Trial Details

FieldValue
Enrollment Target 55 participants
Start Date 2022-01-24
Est. Completion 2025-05-02
Phase Phase 1

Sponsor

Biomea Fusion

9 total trials

What the Registry Record Tells You About NCT05153330

The ClinicalTrials.gov registry entry for NCT05153330 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 55 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Biomea Fusion, which has 9 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which BMF-219 is the first listed.

NCT05153330 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05153330 about?

NCT05153330 is a clinical study titled "Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLL". A Phase 1 first-in-human dose-escalation and dose-expansion study of BMF-219, an oral covalent menin inhibitor, in adult patients with AML, ALL (with KMT2A/ MLL1r, NPM1 mutations), DLBCL, MM, and CLL/SLL.

What is the current status of trial NCT05153330?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 55 participants. The study started on 2022-01-24. Estimated completion is 2025-05-02.

What interventions are being tested in trial NCT05153330?

The interventions under investigation include: BMF-219 (DRUG).

Who is sponsoring clinical trial NCT05153330?

This trial is sponsored by Biomea Fusion, which has 9 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.