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NCT05147428 · ClinicalTrials.gov registry record · NA
A Program to Reduce Inappropriate Medications Among Older Adults With Alzheimer's Disease
A NA study, sponsored by University of Massachusetts, Worcester.
- Completed
- Registry status
- NA
- Development phase
- 14,442
- Enrollment target
NCT05147428 is a NA study that has completed, run by University of Massachusetts, Worcester. The registered enrollment target is 14,442 participants.
The verdict
NCT05147428, a NA study, has completed, sponsored by University of Massachusetts, Worcester.
- COMPLETED
- Registry status
- NA
- Development phase
- 14,442 participants
- Enrollment target
Study Summary
Potentially inappropriate prescribing includes the use of medications that may no longer be necessary or that may increase the risk of harm. Inappropriate prescribing can increase the overall symptom burden, and negatively affect health-related quality of life and function. The inappropriate prescription of certain drug categories such as sedative/hypnotics, antipsychotics, and strong anticholinergic agents poses particular risks for older adults, and may be more common among those with Alzheimer's disease and Alzheimer's disease- related dementias (AD/ADRD) due to a higher prevalence of multimorbidity and more frequent prescription of five or more medications. The D-PRESCRIBE-AD (Developing a PRogram to Educate and Sensitize Caregivers to Reduce the Inappropriate Prescription Burden in Elderly with Alzheimer's Disease) study will test a health plan-based intervention using the NIH Collaboratory's Distributed Research Network, which employs the Food and Drug Administration (FDA) Sentinel System infrastructure. The overarching goal of this randomized controlled trial is to assess the effect of a patient/caregiver- centered, multifaceted educational intervention on potentially inappropriate prescribing in patients with AD/ADRD. The research hypothesis is that education on inappropriate prescribing among patients/caregivers and their providers can reduce medication-related morbidity in patients with AD/ADRD and improve medication safety for this vulnerable population. The study population will include community-dwelling patients with AD/ADRD, identified based on diagnoses codes of AD/ADRD or use of a medication for Alzheimer's Disease, who have evidence of potentially inappropriate prescribing the three drug classes above. The trial will evaluate the effect of educational interventions designed to spur patient/caregiver-provider communication about medication safety (versus usual care) on the proportion of patients with inappropriate prescribing, the primary outcome of
Interventions
- OTHER Educational Materials
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14,442 participants |
| Start Date | 2022-06-01 |
| Est. Completion | 2023-10-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05147428
The ClinicalTrials.gov registry entry for NCT05147428 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 14,442 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Massachusetts, Worcester, which has 240 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Educational Materials is the first listed.
NCT05147428 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT05147428 about?
NCT05147428 is a clinical study titled "A Program to Reduce Inappropriate Medications Among Older Adults With Alzheimer's Disease". Potentially inappropriate prescribing includes the use of medications that may no longer be necessary or that may increase the risk of harm. Inappropriate prescribing can increase the overall symptom burden, and negatively affect health-related quality of life and function. The inappropriate prescri...
What is the current status of trial NCT05147428?
This trial is currently completed. It is a NA study. The enrollment target is 14,442 participants. The study started on 2022-06-01. Estimated completion is 2023-10-01.
What interventions are being tested in trial NCT05147428?
The interventions under investigation include: Educational Materials (OTHER).
Who is sponsoring clinical trial NCT05147428?
This trial is sponsored by University of Massachusetts, Worcester, which has 240 total clinical trials registered on ClinicalTrials.gov.
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