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NCT05140382 · ClinicalTrials.gov registry record · Phase 2

AZD4573 as Monotherapy or in Combinations With Anti-cancer Agents in Patients With r/r PTCL or r/r cHL

A Phase 2 study, sponsored by AstraZeneca.

Completed
Registry status
Phase 2
Development phase
52
Enrollment target

NCT05140382 is a Phase 2 study that has completed, run by AstraZeneca. The registered enrollment target is 52 participants.

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The verdict

NCT05140382, a Phase 2 study, has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
Phase 2
Development phase
52 participants
Enrollment target

Study Summary

This is a modular dose confirmation and expansion study. The core study design is to assess the efficacy of AZD4573, administered as monotherapy or combination therapy, to participants with either r/r PTCL or r/r cHL and to confirm the safety profiles and PK in these populations. Module 1 of this study will evaluate the efficacy, safety, and tolerability of AZD4573 monotherapy in participants with r/r PTCL or r/r cHL. If AZD4573 monotherapy is found to have promising anti-tumour efficacy in Module 1, an AZD4573 monotherapy Phase II expansion may be added via a substantial protocol amendment.

Interventions

  • DRUG AZD4573

Trial Details

FieldValue
Enrollment Target 52 participants
Start Date 2021-12-15
Est. Completion 2024-02-16
Phase Phase 2

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT05140382

The ClinicalTrials.gov registry entry for NCT05140382 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which AZD4573 is the first listed.

NCT05140382 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05140382 about?

NCT05140382 is a clinical study titled "AZD4573 as Monotherapy or in Combinations With Anti-cancer Agents in Patients With r/r PTCL or r/r cHL". This is a modular dose confirmation and expansion study. The core study design is to assess the efficacy of AZD4573, administered as monotherapy or combination therapy, to participants with either r/r PTCL or r/r cHL and to confirm the safety profiles and PK in these populations. Module 1 of this st...

What is the current status of trial NCT05140382?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 52 participants. The study started on 2021-12-15. Estimated completion is 2024-02-16.

What interventions are being tested in trial NCT05140382?

The interventions under investigation include: AZD4573 (DRUG).

Who is sponsoring clinical trial NCT05140382?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.