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NCT05139797 · ClinicalTrials.gov registry record
Artificial Intelligence Guided Echocardiographic Screening of Rare Diseases (EchoNet-Screening)
A clinical trial of Cardiac Amyloidosis, sponsored by Cedars-Sinai Medical Center.
- Recruiting
- Registry status
- 300
- Enrollment target
- 1
- Study location
NCT05139797: Recruiting study of Cardiac Amyloidosis, sponsored by Cedars-Sinai Medical Center.
NCT05139797 is a study of Cardiac Amyloidosis that is actively recruiting participants, run by Cedars-Sinai Medical Center. The registered enrollment target is 300 participants, below the 917-participant average among 8 other Cardiac Amyloidosis trials with a reported enrollment target (67% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05139797, a study of Cardiac Amyloidosis, is actively recruiting participants, sponsored by Cedars-Sinai Medical Center.
- RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
Despite rapidly advancing developments in targeted therapeutics and genetic sequencing, persistent limits in the accuracy and throughput of clinical phenotyping has led to a widening gap between the potential and the actual benefits realized by precision medicine. Recent advances in machine learning and image processing techniques have shown that machine learning models can identify features unrecognized by human experts and more precisely/accurately assess common measurements made in clinical practice. The investigators have developed an algorithm, termed EchoNet-LVH, to identify cardiac hypertrophy and identify patients who would benefit from additional screening for cardiac amyloidosis and will prospectively evaluate its accuracy in identifying patients whom would benefit from additional screening for cardiac amyloidosis.
Primary Outcome
From chart review, identification of patients who have a downstream diagnosis of cardiac amyloidosis
Conditions Studied
Interventions
- OTHER EchoNet-LVH screening for cardiac amyloidosis
Study Locations (1)
California
- Cedars-Sinai Medical Centre (Los Angeles) - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2021-11-18 |
| Est. Completion | 2027-06-01 |
What NCT05139797 shows while recruiting
NCT05139797 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 917-participant average among 8 other Cardiac Amyloidosis trials with a reported enrollment target (67% lower).
The record links to 1 condition, with Cardiac Amyloidosis appearing as the primary indexed condition, and to 1 intervention - of which EchoNet-LVH screening for cardiac amyloidosis is the first listed.
NCT05139797 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05139797 about?
NCT05139797 is a clinical study titled "Artificial Intelligence Guided Echocardiographic Screening of Rare Diseases (EchoNet-Screening)". Despite rapidly advancing developments in targeted therapeutics and genetic sequencing, persistent limits in the accuracy and throughput of clinical phenotyping has led to a widening gap between the potential and the actual benefits realized by precision medicine. Recent advances in machine learnin...
What is the current status of trial NCT05139797?
This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2021-11-18. Estimated completion is 2027-06-01.
What conditions does trial NCT05139797 study?
This clinical trial studies the following conditions: Cardiac Amyloidosis.
What interventions are being tested in trial NCT05139797?
The interventions under investigation include: EchoNet-LVH screening for cardiac amyloidosis (OTHER).
Who is sponsoring clinical trial NCT05139797?
This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05139797 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiac Amyloidosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05139797's enrollment target sits among peer trials
300 3rd of 8 higher than 6 of 8 other Cardiac Amyloidosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiac Amyloidosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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