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NCT05120908 · ClinicalTrials.gov registry record
Discrimination and the Brain-Gut-Microbiome (BGM) Axis
A clinical trial, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- 266
- Enrollment target
NCT05120908: Completed study, sponsored by University of California, Los Angeles.
NCT05120908 is a clinical trial that has completed, run by University of California, Los Angeles. The registered enrollment target is 266 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05120908 has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- 266 participants
- Enrollment target
Study Summary
Obesity is a major public health problem related to a variety of illnesses such as heart disease and diabetes. Prior research indicates that social stressors contribute to risk for obesity, possibly through alterations in diet and physical activity. However, it is not fully clear how these alterations contribute to obesity. The purpose of this study is to examine how the stressors of social isolation and discrimination relate to eating behaviors and dietary patterns, and further, how these behaviors affect the brain-gut-microbiome (BGM) connections. This study will focus on Mexican and Filipina women because research shows that they encounter a high burden of obesity and exposure to social stressors. Approximately 300 Mexican and Filipina women will be screened and enrolled. They will then provide information about social stressors via food diaries, physical body measures (e.g. waist circumference), questionnaire data regarding diet and eating behaviors, and measures of physical activity. Stool and serum will be collected to analyze microbes and metabolomics, and MRI to assess brain changes in the reward network. Analytic techniques will be used to integrate data from these multiple data sources. This analysis will determine the unique differences associated with ethnicity and social stressors in moderating eating behaviors and dietary patterns. The results of this study will provide new information about a possible pathway whereby social stressors affect behavioral, neurological and microbiome mechanisms related to obesity risk and provide new information in BGM patterns in two understudied ethnic groups. In the long term, this research may suggest possible approaches for intervention that may help reduce inequalities in obesity and related health problems.
Primary Outcome
Neuroimaging of participants brain via MRI procedure.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 266 participants |
| Start Date | 2021-08-24 |
| Est. Completion | 2024-12-31 |
What the finished NCT05120908 record still lists
NCT05120908 is an observational study that tracks outcomes without assigning an intervention. The registered 266 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT05120908 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05120908 about?
NCT05120908 is a clinical study titled "Discrimination and the Brain-Gut-Microbiome (BGM) Axis". Obesity is a major public health problem related to a variety of illnesses such as heart disease and diabetes. Prior research indicates that social stressors contribute to risk for obesity, possibly through alterations in diet and physical activity. However, it is not fully clear how these alteratio...
What is the current status of trial NCT05120908?
This trial is currently completed. The enrollment target is 266 participants. The study started on 2021-08-24. Estimated completion is 2024-12-31.
Who is sponsoring clinical trial NCT05120908?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
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