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NCT05117008 · ClinicalTrials.gov registry record · Phase 2

Maintenance Belantamab Mafodotin (Blenrep®) After B-cell Maturation Antigen-Directed Chimeric Antigen Receptor T-cell Therapy in Patients With Relapsed and/or Refractory Multiple Myeloma

A Phase 2 study, sponsored by Medical College of Wisconsin.

Terminated
Registry status
Phase 2
Development phase
1
Enrollment target

NCT05117008 is a Phase 2 study that was terminated before completion, run by Medical College of Wisconsin. The registered enrollment target is 1 participants.

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The verdict

NCT05117008, a Phase 2 study, was terminated before completion, sponsored by Medical College of Wisconsin.

TERMINATED
Registry status
Phase 2
Development phase
1 participants
Enrollment target

Study Summary

This is a multicenter phase II, open-label study evaluating the efficacy and safety of belantamab mafodotin maintenance in participants with relapsed and/or refractory multiple myeloma (RRMM) who have received commercially available anti-BCMA CAR-T-cell therapy. Subjects will be enrolled 60-130 days after chimeric antigen receptor T-cell therapy (CAR-T) and receive belantamab mafodotin as maintenance therapy. Each maintenance cycle will have a duration of 56 days (+/- three days) and belantamab mafodotin will be administered at a dose of 2.5 mg/kg IV on day 1 of each cycle.

Interventions

  • DRUG Belantamab mafodotin

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2022-07-19
Est. Completion 2024-01-15
Phase Phase 2

Sponsor

Medical College of Wisconsin

447 total trials

What the Registry Record Tells You About NCT05117008

The ClinicalTrials.gov registry entry for NCT05117008 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 1 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical College of Wisconsin, which has 447 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Belantamab mafodotin is the first listed.

NCT05117008 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05117008 about?

NCT05117008 is a clinical study titled "Maintenance Belantamab Mafodotin (Blenrep®) After B-cell Maturation Antigen-Directed Chimeric Antigen Receptor T-cell Therapy in Patients With Relapsed and/or Refractory Multiple Myeloma". This is a multicenter phase II, open-label study evaluating the efficacy and safety of belantamab mafodotin maintenance in participants with relapsed and/or refractory multiple myeloma (RRMM) who have received commercially available anti-BCMA CAR-T-cell therapy. Subjects will be enrolled 60-130 days...

What is the current status of trial NCT05117008?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 1 participants. The study started on 2022-07-19. Estimated completion is 2024-01-15.

What interventions are being tested in trial NCT05117008?

The interventions under investigation include: Belantamab mafodotin (DRUG).

Who is sponsoring clinical trial NCT05117008?

This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.