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NCT05113901 · ClinicalTrials.gov registry record · Phase 4
Medrol Dosepak Taper for Delayed Post-op Recovery After TKA
A Phase 4 study, sponsored by Rush University Medical Center.
- Terminated
- Registry status
- Phase 4
- Development phase
- 4
- Enrollment target
NCT05113901: Clinical Trial Phase 4 study, sponsored by Rush University Medical Center.
NCT05113901 is a Phase 4 study that was terminated before completion, run by Rush University Medical Center. The registered enrollment target is 4 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05113901, a Phase 4 study, was terminated before completion, sponsored by Rush University Medical Center.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 4 participants
- Enrollment target
Study Summary
To evaluate the efficacy of a methylprednisolone taper on patients with decreased range of motion (ROM) or delayed recovery in the acute postoperative period following total knee arthroplasty (TKA). Patients with decreased ROM or delayed recovery six weeks to three months post-TKA will improve ROM and patient-reported outcomes at two weeks post-treatment initiation of methylprednisolone taper, as compared to similar patients who receive a placebo taper.
Primary Outcome
Range of motion (ROM) from pre-treatment to six weeks following treatment. Patients started treatment after total knee replacement surgery and presented to clinic with at least one inclusion criteria to be enrolled. Range of motion in degrees is taken at each visit by a clinician (standard of care), starting at zero degrees (straight leg) to about 135 degrees. The ROM was documented as part of consenting and enrollment into study. Subjects returned to the office at 6 weeks post treatment where R
Interventions
- DRUG Placebo
- DRUG Methylprednisolone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2022-03-03 |
| Est. Completion | 2022-07-25 |
| Phase | Phase 4 |
Why NCT05113901 stopped before completion
NCT05113901 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT05113901 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05113901 about?
NCT05113901 is a clinical study titled "Medrol Dosepak Taper for Delayed Post-op Recovery After TKA". To evaluate the efficacy of a methylprednisolone taper on patients with decreased range of motion (ROM) or delayed recovery in the acute postoperative period following total knee arthroplasty (TKA). Patients with decreased ROM or delayed recovery six weeks to three months post-TKA will improve ROM ...
What is the current status of trial NCT05113901?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 4 participants. The study started on 2022-03-03. Estimated completion is 2022-07-25.
What interventions are being tested in trial NCT05113901?
The interventions under investigation include: Placebo (DRUG), Methylprednisolone (DRUG).
Who is sponsoring clinical trial NCT05113901?
This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05113901's enrollment target sits among peer trials
4 1994th of 2000 higher than 6 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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