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NCT05110274 · ClinicalTrials.gov registry record · NA
Validating a Novel Approach to Assess Metabolic Flexibility in a Respiratory Chamber
A NA study, sponsored by Pennington Biomedical Research Center.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT05110274: Completed NA study, sponsored by Pennington Biomedical Research Center.
NCT05110274 is a NA study that has completed, run by Pennington Biomedical Research Center. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05110274, a NA study, has completed, sponsored by Pennington Biomedical Research Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
This study is designed to test the reliability of a novel procedure for measuring metabolic flexibility, i.e., the ability to quickly adapt macronutrient oxidation to macronutrient availability, in a respiratory chamber. The investigators will compare paired measurements of metabolic flexibility determined 5-7 days apart in a metabolic chamber to assess reliability. The investigators will also compare their novel method of measuring metabolic flexibility in a respiratory chamber with a more convention method, metabolic flexibility during a hyperinsulinemic clamp.
Primary Outcome
mean of peak decrease in respiratory exchange ratio (baseline values -nadir values) following the test meal during an overnight stay in a respiratory chamber. Peak values are defined as the lowest respiratory exchange ratio value measured during the sleep period, 11pm-5am Baseline values are measured 1h prior to meal (5:00-5:45pm) An increase in this value indicates increased metabolic flexibility.
Interventions
- PROCEDURE Overnight Metabolic Flexibility
- PROCEDURE Clamp Metabolic Flexibility
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2021-08-26 |
| Est. Completion | 2022-07-08 |
| Phase | NA |
What the finished NCT05110274 record still lists
NCT05110274 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Overnight Metabolic Flexibility is the first listed.
NCT05110274 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05110274 about?
NCT05110274 is a clinical study titled "Validating a Novel Approach to Assess Metabolic Flexibility in a Respiratory Chamber". This study is designed to test the reliability of a novel procedure for measuring metabolic flexibility, i.e., the ability to quickly adapt macronutrient oxidation to macronutrient availability, in a respiratory chamber. The investigators will compare paired measurements of metabolic flexibility det...
What is the current status of trial NCT05110274?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2021-08-26. Estimated completion is 2022-07-08.
What interventions are being tested in trial NCT05110274?
The interventions under investigation include: Overnight Metabolic Flexibility (PROCEDURE), Clamp Metabolic Flexibility (PROCEDURE).
Who is sponsoring clinical trial NCT05110274?
This trial is sponsored by Pennington Biomedical Research Center, which has 258 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05110274's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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