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NCT05109390 · ClinicalTrials.gov registry record · Phase 1
A Study of the Drug Interactions Between Danicopan and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy Adults
A Phase 1 study, sponsored by Alexion Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 72
- Enrollment target
NCT05109390: Completed Phase 1 study, sponsored by Alexion Pharmaceuticals.
NCT05109390 is a Phase 1 study that has completed, run by Alexion Pharmaceuticals. The registered enrollment target is 72 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05109390, a Phase 1 study, has completed, sponsored by Alexion Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 72 participants
- Enrollment target
Study Summary
This was a 3-part study with each part being an open-label, fixed-sequence, 2-period study in healthy adult participants.
Interventions
- DRUG Tacrolimus
- DRUG Cyclosporine
- DRUG Danicopan
- DRUG Calcium Carbonate
- DRUG Aluminum/Magnesium Hydroxide/Simethicone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2018-07-27 |
| Est. Completion | 2018-10-17 |
| Phase | Phase 1 |
What the finished NCT05109390 record still lists
NCT05109390 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% higher).
The record links to 0 conditions, and to 5 interventions - of which Tacrolimus is the first listed.
NCT05109390 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05109390 about?
NCT05109390 is a clinical study titled "A Study of the Drug Interactions Between Danicopan and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy Adults". This was a 3-part study with each part being an open-label, fixed-sequence, 2-period study in healthy adult participants.
What is the current status of trial NCT05109390?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 72 participants. The study started on 2018-07-27. Estimated completion is 2018-10-17.
What interventions are being tested in trial NCT05109390?
The interventions under investigation include: Tacrolimus (DRUG), Cyclosporine (DRUG), Danicopan (DRUG), Calcium Carbonate (DRUG), Aluminum/Magnesium Hydroxide/Simethicone (DRUG).
Who is sponsoring clinical trial NCT05109390?
This trial is sponsored by Alexion Pharmaceuticals, which has 162 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05109390's enrollment target sits among peer trials
72 736th of 2000 higher than 1,254 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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