Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05092919 · ClinicalTrials.gov registry record · Early Phase 1

The Effect of Sweet Flavoring on the Rewarding and Reinforcing Value of Cigarillo Use Among Young Adults

A Early Phase 1 study, sponsored by University of Pennsylvania.

Completed
Registry status
Early Phase 1
Development phase
95
Enrollment target

NCT05092919: Completed Early Phase 1 study, sponsored by University of Pennsylvania.

NCT05092919 is a Early Phase 1 study that has completed, run by University of Pennsylvania. The registered enrollment target is 95 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (79% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT05092919, a Early Phase 1 study, has completed, sponsored by University of Pennsylvania.

COMPLETED
Registry status
Early Phase 1
Development phase
95 participants
Enrollment target

Study Summary

This within-subjects study aims to evaluate the subjective rewarding value, the relative reinforcing value, and the absolute reinforcing value of sweet flavored cigarillos across three separate laboratory visits among 86 young adults (ages 18-24 years old) who have previously smoked \> 10 or more cigarillos in their lifetime.

Primary Outcome

Subjective rewarding value of cigarillo flavoring will be measured with the Cigarette Evaluation Scale (CES) adapted for cigarillo use. The CES is an 11 item Likert-format (1=not at all to 7=extremely) self-report instrument with established validity and reliability (α \> .80). The investigators will focus on the sum of the two-item satisfaction subscale ("Was it satisfying?" and "Did it taste good?") to calculate the subjective rewarding value. The minimum possible score is 2 and the maximum is

Interventions

  • OTHER Flavor

Trial Details

FieldValue
Enrollment Target 95 participants
Start Date 2021-09-14
Est. Completion 2023-05-31
Phase Early Phase 1
University of Pennsylvania

1,423 total trials

What the finished NCT05092919 record still lists

NCT05092919 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 95 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (79% higher).

The record links to 0 conditions, and to 1 intervention - of which Flavor is the first listed.

NCT05092919 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05092919 about?

NCT05092919 is a clinical study titled "The Effect of Sweet Flavoring on the Rewarding and Reinforcing Value of Cigarillo Use Among Young Adults". This within-subjects study aims to evaluate the subjective rewarding value, the relative reinforcing value, and the absolute reinforcing value of sweet flavored cigarillos across three separate laboratory visits among 86 young adults (ages 18-24 years old) who have previously smoked \> 10 or more ci...

What is the current status of trial NCT05092919?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 95 participants. The study started on 2021-09-14. Estimated completion is 2023-05-31.

What interventions are being tested in trial NCT05092919?

The interventions under investigation include: Flavor (OTHER).

Who is sponsoring clinical trial NCT05092919?

This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05092919's enrollment target sits among peer trials

95 226th of 2000 higher than 1,774 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03339128 · 95 participants · Phase 2

    Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children

  • NCT03509961 · 95 participants · Phase 2

    The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL

  • NCT03694756 · 95 participants · NA

    TMEM-MRI: A Pilot Feasibility Study of MRI for Imaging of TMEM in Patients With Operable Breast Cancer

  • NCT04206215 · 95 participants · NA

    Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05092919, the US trial registry maintained by the National Library of Medicine. NCT05092919 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.