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NCT05087550 · ClinicalTrials.gov registry record

Multicenter Study on Organ Acquisition Costs in the Post Re-Allocation Era: Liver Transplantation

A clinical trial, sponsored by Methodist Health System.

Completed
Registry status
186
Enrollment target

NCT05087550 is a clinical trial that has completed, run by Methodist Health System. The registered enrollment target is 186 participants.

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The verdict

NCT05087550 has completed, sponsored by Methodist Health System.

COMPLETED
Registry status
186 participants
Enrollment target

Study Summary

Organ procurement organizations (OPO) have increased organ recovery efficiency and yield and have also reduced organ acquisition charges. The new liver allocation policy came into effect in February 2020 and aims to increase access to organs for waitlist candidates with the greatest severity of illness. The urgent change was driven by the perception that patients were dying because of arbitrary boundaries and inequitable access. Critics of the new policy have highlighted the potential cost implications particularly at an OPO level. A study of five OPOs throughout the United States highlighted an increase in costs ranging from 43% - 206% despite the same volume of livers transplanted. The main reason for the cost appears to lie in organ handling and transport. This mirrors the findings of Puri and colleagues who acknowledged changes to lung transplantation at Barnes Jewish Hospital in the pre- and post-policy eras and reported a substantial decline in local donors. The new lung system has also resulted in a higher organ discard rate and ultimately higher costs. Such data has generated meaningful discussions regarding optimizing organ allocation polices, however, data from individual transplant centers is lacking in the literature. Changes at a transplant center level relating to recipient costs are likely impacted by the new policy, which could be related to patient travel, accommodation, work up etc.

Interventions

  • PROCEDURE Liver Transplantation

Trial Details

FieldValue
Enrollment Target 186 participants
Start Date 2021-10-13
Est. Completion 2023-08-09

Sponsor

Methodist Health System

125 total trials

What the Registry Record Tells You About NCT05087550

The ClinicalTrials.gov registry entry for NCT05087550 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 186 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Methodist Health System, which has 125 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Liver Transplantation is the first listed.

NCT05087550 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05087550 about?

NCT05087550 is a clinical study titled "Multicenter Study on Organ Acquisition Costs in the Post Re-Allocation Era: Liver Transplantation". Organ procurement organizations (OPO) have increased organ recovery efficiency and yield and have also reduced organ acquisition charges. The new liver allocation policy came into effect in February 2020 and aims to increase access to organs for waitlist candidates with the greatest severity of illn...

What is the current status of trial NCT05087550?

This trial is currently completed. The enrollment target is 186 participants. The study started on 2021-10-13. Estimated completion is 2023-08-09.

What interventions are being tested in trial NCT05087550?

The interventions under investigation include: Liver Transplantation (PROCEDURE).

Who is sponsoring clinical trial NCT05087550?

This trial is sponsored by Methodist Health System, which has 125 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.