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NCT05085613 · ClinicalTrials.gov registry record · NA

Does Framing and Humor Improve the Effectiveness of Messages About COVID-19 Vaccine

A NA study, sponsored by Johns Hopkins Bloomberg School of Public Health.

Completed
Registry status
NA
Development phase
100
Enrollment target

NCT05085613: Completed NA study, sponsored by Johns Hopkins Bloomberg School of Public Health.

NCT05085613 is a NA study that has completed, run by Johns Hopkins Bloomberg School of Public Health. The registered enrollment target is 100 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05085613, a NA study, has completed, sponsored by Johns Hopkins Bloomberg School of Public Health.

COMPLETED
Registry status
NA
Development phase
100 participants
Enrollment target

Study Summary

This study seeks to assess the efficacy of educational messages to correct misperceptions. People hold a number of misperceptions that are relevant to public health, including misperceptions regarding COVID vaccines. Some people incorrectly think the COVID vaccines authorized by FDA are not safe or effective. These misperceptions can reduce adherence to public health recommendations and result in continued spread of COVID. This study will test if humor and different types of framing increase the efficacy of messages to correct misperceptions about FDA's authorized coronavirus vaccine safety and effectiveness. The frames tested will include: framing the vaccine as a way to boost economic recovery and framing the vaccine as a way to increase freedom to choose how to behave. The addition of humor will also be tested. Message efficacy will be measured via improved accuracy of beliefs after being exposed to the message. In other words, participants will be asked how safe and effective FDA authorized COVID vaccines are before seeing a message, then they will see a message about why the COVID vaccines are safe and effective, and then they will again be asked how safe and effective they think the vaccines are. This study will also assess the accuracy of inferential beliefs. This will be accomplished by asking participants questions about other vaccines that either are or are not authorized by FDA. If participants have understood the messages and updated their mental models of how FDA evaluates vaccines, they should be able to infer if other vaccines are safe and effective based on their FDA authorization status. Hypotheses H1: Participants who are exposed to A.) a message with humor, B.) a message with an economic recovery fame, or C.) a message with a freedom frame will be more likely to increase their agreement with the statement that the FDA will only authorize coronavirus vaccines that are safe and effective after message exposure than participants exposed to the cont

Primary Outcome

Assessed by change in response to the question To what extent do you agree or disagree with the following statement: The FDA has only authorized COVID vaccines that are safe and effective; with response options on a continuous scale from 0 "I do not agree at all" to 100, "I completely agree."

Interventions

  • BEHAVIORAL Corrective message framing and humor

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2021-10-31
Est. Completion 2022-03-31
Phase NA

What the finished NCT05085613 record still lists

NCT05085613 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).

The record links to 0 conditions, and to 1 intervention - of which Corrective message framing and humor is the first listed.

NCT05085613 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05085613 about?

NCT05085613 is a clinical study titled "Does Framing and Humor Improve the Effectiveness of Messages About COVID-19 Vaccine". This study seeks to assess the efficacy of educational messages to correct misperceptions. People hold a number of misperceptions that are relevant to public health, including misperceptions regarding COVID vaccines. Some people incorrectly think the COVID vaccines authorized by FDA are not safe or ...

What is the current status of trial NCT05085613?

This trial is currently completed. It is a NA study. The enrollment target is 100 participants. The study started on 2021-10-31. Estimated completion is 2022-03-31.

What interventions are being tested in trial NCT05085613?

The interventions under investigation include: Corrective message framing and humor (BEHAVIORAL).

Who is sponsoring clinical trial NCT05085613?

This trial is sponsored by Johns Hopkins Bloomberg School of Public Health, which has 187 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05085613's enrollment target sits among peer trials

100 840th of 2000 higher than 1,081 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05085613, the US trial registry maintained by the National Library of Medicine. NCT05085613 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.