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NCT05066672 · ClinicalTrials.gov registry record · Phase 2
Phase 2 Study of NV-5138 in Adults With Treatment Resistant Depression
A Phase 2 study, sponsored by Navitor Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 250
- Enrollment target
NCT05066672: Completed Phase 2 study, sponsored by Navitor Pharmaceuticals.
NCT05066672 is a Phase 2 study that has completed, run by Navitor Pharmaceuticals. The registered enrollment target is 250 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (88% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05066672, a Phase 2 study, has completed, sponsored by Navitor Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 250 participants
- Enrollment target
Study Summary
This study will evaluate the efficacy and safety of NV-5138 in adults with TRD
Primary Outcome
MADRS is a 10-item scale (Reported sadness, Apparent sadness, Inner tension, Reduced sleep, Reduced appetite, Concentration difficulties, Lassitude, Inability to feel, Pessimist thoughts, and Suicidal thoughts) where each item is scored from 0 to 6. The total score is the sum of the 10 items ranging from 0 to 60 where higher scores indicate more severe depression, and lower scores are better outcomes. A negative change from baseline indicates improvement in depressive symptoms.
Interventions
- DRUG NV-5138
- DRUG matched placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 250 participants |
| Start Date | 2022-01-18 |
| Est. Completion | 2025-01-21 |
| Phase | Phase 2 |
What the finished NCT05066672 record still lists
NCT05066672 is an interventional study that assigns participants to a tested intervention. The registered 250 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (88% higher).
The record links to 0 conditions, and to 2 interventions - of which NV-5138 is the first listed.
NCT05066672 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05066672 about?
NCT05066672 is a clinical study titled "Phase 2 Study of NV-5138 in Adults With Treatment Resistant Depression". This study will evaluate the efficacy and safety of NV-5138 in adults with TRD
What is the current status of trial NCT05066672?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 250 participants. The study started on 2022-01-18. Estimated completion is 2025-01-21.
What interventions are being tested in trial NCT05066672?
The interventions under investigation include: NV-5138 (DRUG), matched placebo (DRUG).
Who is sponsoring clinical trial NCT05066672?
This trial is sponsored by Navitor Pharmaceuticals, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05066672's enrollment target sits among peer trials
250 222nd of 2000 higher than 1,768 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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