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NCT05062785 · ClinicalTrials.gov registry record · Phase 1
Dose-Finding Study of Intranasal Insulin in Healthy Participants Insulin in Healthy Participants
A Phase 1 study, sponsored by Robert Silbergleit.
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
NCT05062785: Completed Phase 1 study, sponsored by Robert Silbergleit.
NCT05062785 is a Phase 1 study that has completed, run by Robert Silbergleit. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05062785, a Phase 1 study, has completed, sponsored by Robert Silbergleit.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
This study is to determine the safety and tolerability of regular insulin (Humulin R) when given intranasally (as drops in nostrils). Healthy participants will be enrolled to determine the maximum tolerated dose of intranasal insulin.
Primary Outcome
Results reflect the participants who experienced severe hypoglycemia generically at the time they received a dose of insulin, as defined by blood glucose \< 45 milligrams per deciliter (mg/dL). Severe hypoglycemia was considered a dose limiting toxicity (DLT).
Interventions
- DRUG Intranasal insulin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2021-10-04 |
| Est. Completion | 2022-04-25 |
| Phase | Phase 1 |
What the finished NCT05062785 record still lists
NCT05062785 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 1 intervention - of which Intranasal insulin is the first listed.
NCT05062785 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05062785 about?
NCT05062785 is a clinical study titled "Dose-Finding Study of Intranasal Insulin in Healthy Participants Insulin in Healthy Participants". This study is to determine the safety and tolerability of regular insulin (Humulin R) when given intranasally (as drops in nostrils). Healthy participants will be enrolled to determine the maximum tolerated dose of intranasal insulin.
What is the current status of trial NCT05062785?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2021-10-04. Estimated completion is 2022-04-25.
What interventions are being tested in trial NCT05062785?
The interventions under investigation include: Intranasal insulin (DRUG).
Who is sponsoring clinical trial NCT05062785?
This trial is sponsored by Robert Silbergleit, which has 2 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05062785's enrollment target sits among peer trials
24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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