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Long-Term Follow-Up Study of AAV2hAQP1 for Radiation Induced Xerostomia
NCT05060341 · View on ClinicalTrials.gov ↗
Study Summary
This study is a long-term follow-up study for patients who have been administered AAV2hAQP1 in the Phase 1 Open-Label, Dose Escalation Study to Determine the Optimal Dose, Safety, and Activity in Subjects with Radiation Induced Parotid Gland Hypofunction and Xerostomia
Conditions Studied
Study Locations (4)
California
- Leland Stanford Junior University — Stanford
Massachusetts
- Brigham and Women's Hospital — Boston
North Carolina
- Atrium Health — Charlotte
Ontario
- Health Sciences North - Northeast Cancer Center — Greater Sudbury
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2020-11-12 |
| Est. Completion | 2027-03 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05060341
The ClinicalTrials.gov registry entry for NCT05060341 describes a study currently listed as active not recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is MeiraGTx, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Radiation-induced Xerostomia appearing as the primary indexed condition, and to 0 interventions. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05060341 reports 4 study locations spanning 4 distinct geographic areas — top geographies include California, Massachusetts, North Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05060341 about?
NCT05060341 is a clinical study titled "Long-Term Follow-Up Study of AAV2hAQP1 for Radiation Induced Xerostomia". This study is a long-term follow-up study for patients who have been administered AAV2hAQP1 in the Phase 1 Open-Label, Dose Escalation Study to Determine the Optimal Dose, Safety, and Activity in Subjects with Radiation Induced Parotid Gland Hypofunction and Xerostomia
What is the current status of trial NCT05060341?
This trial is currently active not recruiting. The enrollment target is 22 participants. The study started on 2020-11-12. Estimated completion is 2027-03.
What conditions does trial NCT05060341 study?
This clinical trial studies the following conditions: Radiation-induced Xerostomia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
Who is sponsoring clinical trial NCT05060341?
This trial is sponsored by MeiraGTx, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05060341 being conducted?
This trial has 4 study locations across California, Massachusetts, North Carolina, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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