Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING NA

Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma

NCT05057702 · View on ClinicalTrials.gov ↗

Study Summary

The current study will use a new treatment approach based on the molecular characteristics of each participant's tumor. The study will test the feasibility in the pilot phase of performing real-time drug screening on tissue taken during surgery in patients with relapsed medulloblastoma or ependymoma and of having a specialized tumor board assign a treatment plan based on the results of this screening and genomic sequencing. The aim of this trial is to allow every child and young adult with relapsed medulloblastoma and ependymoma to receive the most effective and least toxic therapies currently available and will pave the way for improved understanding and treatment of these tumors in the future. Moreover, if successful, it could serve as a paradigm for personalized medicine programs for other types of cancer.

Interventions

  • OTHER Specialized Tumor Board Treatment Plan
  • OTHER Combinations

Study Locations (8)

California

  • Children's Hospital of Los Angeles — Los Angeles
  • Rady Children's Hospital — San Diego
  • University of California, San Francisco — San Francisco

New York

  • New York University — New York
  • Columbia University Medical Center — New York

District of Columbia

  • Children's National Hospital — Washington D.C.

Missouri

  • St. Louis Children's Hospital / Washington University in St. Louis — St Louis

Pennsylvania

  • Children's Hospital of Philadelphia — Philadelphia

Trial Details

FieldValue
Enrollment Target 74 participants
Start Date 2022-02-22
Est. Completion 2028-01-31
Phase NA

Sponsor

University of California, San Francis

1,574 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05057702

The ClinicalTrials.gov registry entry for NCT05057702 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 74 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francis, which has 1,574 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 6 conditions, with Medulloblastoma appearing as the primary indexed condition, and to 2 interventions — of which Specialized Tumor Board Treatment Plan is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT05057702 reports 8 study locations spanning 5 distinct geographic areas — top geographies include California, New York, District of Columbia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT05057702 about?

NCT05057702 is a clinical study titled "Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma". The current study will use a new treatment approach based on the molecular characteristics of each participant's tumor. The study will test the feasibility in the pilot phase of performing real-time drug screening on tissue taken during surgery in patients with relapsed medulloblastoma or ependymoma...

What is the current status of trial NCT05057702?

This trial is currently recruiting. It is a NA study. The enrollment target is 74 participants. The study started on 2022-02-22. Estimated completion is 2028-01-31.

What conditions does trial NCT05057702 study?

This clinical trial studies the following conditions: Medulloblastoma, Ependymoma, Medulloblastoma Recurrent, Medulloblastoma, Childhood, Ependymoma Malignant. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT05057702?

The interventions under investigation include: Specialized Tumor Board Treatment Plan (OTHER), Combinations (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT05057702?

This trial is sponsored by University of California, San Francis, which has 1,574 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT05057702 being conducted?

This trial has 8 study locations across California, District of Columbia, Missouri, New York, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial