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NCT05057494 · ClinicalTrials.gov registry record · Phase 3

A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

A Phase 3 study of Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, sponsored by AstraZeneca.

Active
Registry status
Phase 3
Development phase
607
Enrollment target
20
Study locations

NCT05057494 is a Phase 3 study of Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma that is active but no longer recruiting, run by AstraZeneca. The registered enrollment target is 607 participants. The trial reports 20 study locations across 16 states.

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The verdict

NCT05057494, a Phase 3 study of Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, is active but no longer recruiting, sponsored by AstraZeneca.

ACTIVE NOT RECRUITING
Registry status
Phase 3
Development phase
607 participants
Enrollment target
20
Study locations

Study Summary

A study of acalabrutinib plus venetoclax (AV) versus venetoclax plus obinutuzumab (VO) in previously untreated chronic lymphocytic leukemia or small lymphocytic lymphoma.

Interventions

  • DRUG Obinutuzumab
  • DRUG Venetoclax
  • DRUG Acalabrutinib

Study Locations (20)

New York

  • Research Site - Buffalo
  • Research Site - New Hyde Park
  • Research Site - New York
  • Research Site - Rochester

Washington

  • Research Site - Seattle
  • Research Site - Seattle

Arizona

  • Research Site - Tucson

California

  • Research Site - La Jolla

Colorado

  • Research Site - Longmont

Florida

  • Research Site - Jacksonville

Massachusetts

  • Research Site - Boston

Missouri

  • Research Site - St Louis

Trial Details

FieldValue
Enrollment Target 607 participants
Start Date 2022-09-12
Est. Completion 2029-04-10
Phase Phase 3

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT05057494

The ClinicalTrials.gov registry entry for NCT05057494 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 607 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma appearing as the primary indexed condition, and to 3 interventions - of which Obinutuzumab is the first listed.

NCT05057494 reports 20 study locations spanning 16 distinct geographic areas - top geographies include New York, Washington, Arizona.

Frequently Asked Questions

What is clinical trial NCT05057494 about?

NCT05057494 is a clinical study titled "A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma". A study of acalabrutinib plus venetoclax (AV) versus venetoclax plus obinutuzumab (VO) in previously untreated chronic lymphocytic leukemia or small lymphocytic lymphoma.

What is the current status of trial NCT05057494?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 607 participants. The study started on 2022-09-12. Estimated completion is 2029-04-10.

What conditions does trial NCT05057494 study?

This clinical trial studies the following conditions: Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma.

What interventions are being tested in trial NCT05057494?

The interventions under investigation include: Obinutuzumab (DRUG), Venetoclax (DRUG), Acalabrutinib (DRUG).

Who is sponsoring clinical trial NCT05057494?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05057494 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Florida, Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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