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NCT05056597 · ClinicalTrials.gov registry record

Incentive Processing and Learning in Anorexia Nervosa and Bulimia Nervosa

A clinical trial of Anorexia Nervosa and Bulimia Nervosa, sponsored by University of California, San Diego.

Recruiting
Registry status
252
Enrollment target
1
Study location

NCT05056597 is a study of Anorexia Nervosa and Bulimia Nervosa that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 252 participants, below the 944-participant average among 43 other Anorexia Nervosa trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05056597, a study of Anorexia Nervosa and Bulimia Nervosa, is actively recruiting participants, sponsored by University of California, San Diego.

RECRUITING
Registry status
252 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to investigate areas of the brain responsible for 'liking', 'wanting', and learning in adults with eating disorders using brain imaging techniques, computer tasks, a test meal, and self-report questionnaires and interviews. The investigators will study changes in brain activity using a procedure called functional magnetic resonance imaging (fMRI). This study will include 252 women with an eating disorder (63 AN-restricting type (AN-R), 63 AN-binge eating/purging type (AN-BP), 63 bulimia nervosa (BN)) and 63 healthy controls (HC) aged 18-39. Aim 1: To examine neural differences in 'liking' and 'wanting' in ED relative to HC. Aim 2: To examine differences in instrumental learning for reward and punishment in ED relative to HC. Aim 3: To examine how 'liking' and 'wanting' drive instrumental learning in ED and predict clinical symptoms at baseline and 1 year later. Exploratory Aim: To explore the associations of dopamine function, as measured by neuromelanin MRI (NM-MRI), with ED diagnosis and brain response to 'liking', 'wanting', and learning.

Study Locations (1)

California

  • UCSD Eating Disorders Treatment and Research Program - La Jolla

Trial Details

FieldValue
Enrollment Target 252 participants
Start Date 2022-05-26
Est. Completion 2027-01

Sponsor

University of California, San Diego

775 total trials

What the Registry Record Tells You About NCT05056597

The ClinicalTrials.gov registry entry for NCT05056597 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 252 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 944-participant average among 43 other Anorexia Nervosa trials with a reported enrollment target (73% lower). The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Anorexia Nervosa appearing as the primary indexed condition, and to 0 interventions.

NCT05056597 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT05056597 about?

NCT05056597 is a clinical study titled "Incentive Processing and Learning in Anorexia Nervosa and Bulimia Nervosa". The purpose of this study is to investigate areas of the brain responsible for 'liking', 'wanting', and learning in adults with eating disorders using brain imaging techniques, computer tasks, a test meal, and self-report questionnaires and interviews. The investigators will study changes in brain a...

What is the current status of trial NCT05056597?

This trial is currently recruiting. The enrollment target is 252 participants. The study started on 2022-05-26. Estimated completion is 2027-01.

What conditions does trial NCT05056597 study?

This clinical trial studies the following conditions: Anorexia Nervosa, Bulimia Nervosa.

Who is sponsoring clinical trial NCT05056597?

This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05056597 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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