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NCT05056597 · ClinicalTrials.gov registry record
Incentive Processing and Learning in Anorexia Nervosa and Bulimia Nervosa
A clinical trial of Anorexia Nervosa and Bulimia Nervosa, sponsored by University of California, San Diego.
- Recruiting
- Registry status
- 252
- Enrollment target
- 1
- Study location
NCT05056597: Recruiting study of Anorexia Nervosa and Bulimia Nervosa, sponsored by University of California, San Diego.
NCT05056597 is a study of Anorexia Nervosa and Bulimia Nervosa that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 252 participants, below the 944-participant average among 43 other Anorexia Nervosa trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05056597, a study of Anorexia Nervosa and Bulimia Nervosa, is actively recruiting participants, sponsored by University of California, San Diego.
- RECRUITING
- Registry status
- 252 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to investigate areas of the brain responsible for 'liking', 'wanting', and learning in adults with eating disorders using brain imaging techniques, computer tasks, a test meal, and self-report questionnaires and interviews. The investigators will study changes in brain activity using a procedure called functional magnetic resonance imaging (fMRI). This study will include 252 women with an eating disorder (63 AN-restricting type (AN-R), 63 AN-binge eating/purging type (AN-BP), 63 bulimia nervosa (BN)) and 63 healthy controls (HC) aged 18-39. Aim 1: To examine neural differences in 'liking' and 'wanting' in ED relative to HC. Aim 2: To examine differences in instrumental learning for reward and punishment in ED relative to HC. Aim 3: To examine how 'liking' and 'wanting' drive instrumental learning in ED and predict clinical symptoms at baseline and 1 year later. Exploratory Aim: To explore the associations of dopamine function, as measured by neuromelanin MRI (NM-MRI), with ED diagnosis and brain response to 'liking', 'wanting', and learning.
Primary Outcome
Brain activity associated with 'liking', 'wanting', and learning
Conditions Studied
Study Locations (1)
California
- UCSD Eating Disorders Treatment and Research Program - La Jolla
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 252 participants |
| Start Date | 2022-05-26 |
| Est. Completion | 2027-01 |
What NCT05056597 shows while recruiting
NCT05056597 is an observational study that tracks outcomes without assigning an intervention. The registered 252 participants enrollment target is mid-sized for trials with a published cap, below the 944-participant average among 43 other Anorexia Nervosa trials with a reported enrollment target (73% lower).
The record links to 2 conditions, with Anorexia Nervosa appearing as the primary indexed condition, and to 0 interventions.
NCT05056597 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT05056597 about?
NCT05056597 is a clinical study titled "Incentive Processing and Learning in Anorexia Nervosa and Bulimia Nervosa". The purpose of this study is to investigate areas of the brain responsible for 'liking', 'wanting', and learning in adults with eating disorders using brain imaging techniques, computer tasks, a test meal, and self-report questionnaires and interviews. The investigators will study changes in brain a...
What is the current status of trial NCT05056597?
This trial is currently recruiting. The enrollment target is 252 participants. The study started on 2022-05-26. Estimated completion is 2027-01.
What conditions does trial NCT05056597 study?
This clinical trial studies the following conditions: Anorexia Nervosa, Bulimia Nervosa.
Who is sponsoring clinical trial NCT05056597?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05056597 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05056597's enrollment target sits among peer trials
252 4th of 43 higher than 40 of 43 other Anorexia Nervosa trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anorexia Nervosa trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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