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NCT05056051 · ClinicalTrials.gov registry record · NA

Wide-Area Transepithelial Sampling in Endoscopic Eradication Therapy for Barrett's Esophagus

A NA study of Esophageal Cancer and Barrett Esophagus, sponsored by Northwestern University.

Recruiting
Registry status
NA
Development phase
200
Enrollment target
4
Study locations

NCT05056051 is a NA study of Esophageal Cancer and Barrett Esophagus that is actively recruiting participants, run by Northwestern University. The registered enrollment target is 200 participants, below the 497-participant average among 123 other Esophageal Cancer trials with a reported enrollment target (60% lower). The trial reports 4 study locations across 4 states.

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The verdict

NCT05056051, a NA study of Esophageal Cancer and Barrett Esophagus, is actively recruiting participants, sponsored by Northwestern University.

RECRUITING
Registry status
NA
Development phase
200 participants
Enrollment target
4
Study locations

Study Summary

Esophageal cancer is a deadly disease that is becoming increasingly common in the United States. Barrett's esophagus (BE) is a pre-cancerous state that can develop into esophageal cancer, but is highly treatable. Progression of BE to esophageal cancer is still common due to missed diagnosis of Barrett's esophagus recurrence following treatment. Wide-Area Trans-Epithelial Sampling (WATS-3D) is a new technology that uses brush sampling to examine larger areas of the esophagus as compared to conventional biopsies. Preliminary studies show improved detection of cancerous changes in Barrett's esophagus surveillance. The investigators hope to see if the addition of WATS-3D increases the rate of detection of recurrent BE following treatment, which is of the utmost importance since it would allow for earlier re-treatment of disease and ultimately allow for prevention of progression to esophageal cancer.

Interventions

  • DEVICE WATS-3D tissue sampling prior to forceps biopsies
  • DEVICE WATS-3D tissue sampling following forceps biopsies

Study Locations (4)

California

  • University of California, LA - Los Angeles

Colorado

  • University of Colorado - Aurora

Illinois

  • Northwestern Memorial Hospital - Chicago

Missouri

  • Washington University in St. Louis, Barnes Jewish Hospital - St Louis

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2020-10-01
Est. Completion 2025-06-30
Phase NA

Sponsor

Northwestern University

1,209 total trials

What the Registry Record Tells You About NCT05056051

The ClinicalTrials.gov registry entry for NCT05056051 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 497-participant average among 123 other Esophageal Cancer trials with a reported enrollment target (60% lower). The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Esophageal Cancer appearing as the primary indexed condition, and to 2 interventions - of which WATS-3D tissue sampling prior to forceps biopsies is the first listed.

NCT05056051 reports 4 study locations spanning 4 distinct geographic areas - top geographies include California, Colorado, Illinois.

Frequently Asked Questions

What is clinical trial NCT05056051 about?

NCT05056051 is a clinical study titled "Wide-Area Transepithelial Sampling in Endoscopic Eradication Therapy for Barrett's Esophagus". Esophageal cancer is a deadly disease that is becoming increasingly common in the United States. Barrett's esophagus (BE) is a pre-cancerous state that can develop into esophageal cancer, but is highly treatable. Progression of BE to esophageal cancer is still common due to missed diagnosis of Barre...

What is the current status of trial NCT05056051?

This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2020-10-01. Estimated completion is 2025-06-30.

What conditions does trial NCT05056051 study?

This clinical trial studies the following conditions: Esophageal Cancer, Barrett Esophagus.

What interventions are being tested in trial NCT05056051?

The interventions under investigation include: WATS-3D tissue sampling prior to forceps biopsies (DEVICE), WATS-3D tissue sampling following forceps biopsies (DEVICE).

Who is sponsoring clinical trial NCT05056051?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05056051 being conducted?

This trial has 4 study locations across California, Colorado, Illinois, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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