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NCT05054725 · ClinicalTrials.gov registry record · Phase 2

Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies

A Phase 2 study, sponsored by Revolution Medicines.

Completed
Registry status
Phase 2
Development phase
47
Enrollment target

NCT05054725 is a Phase 2 study that has completed, run by Revolution Medicines. The registered enrollment target is 47 participants.

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The verdict

NCT05054725, a Phase 2 study, has completed, sponsored by Revolution Medicines.

COMPLETED
Registry status
Phase 2
Development phase
47 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the antitumor effects of sotorasib and RMC-4630 in subjects with KRASG12C mutant NSCLC

Interventions

  • DRUG Sotorasib
  • DRUG RMC-4630

Trial Details

FieldValue
Enrollment Target 47 participants
Start Date 2021-12-30
Est. Completion 2024-08-29
Phase Phase 2

Sponsor

Revolution Medicines

16 total trials

What the Registry Record Tells You About NCT05054725

The ClinicalTrials.gov registry entry for NCT05054725 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 47 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Revolution Medicines, which has 16 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Sotorasib is the first listed.

NCT05054725 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05054725 about?

NCT05054725 is a clinical study titled "Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies". The purpose of this study is to evaluate the antitumor effects of sotorasib and RMC-4630 in subjects with KRASG12C mutant NSCLC

What is the current status of trial NCT05054725?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 47 participants. The study started on 2021-12-30. Estimated completion is 2024-08-29.

What interventions are being tested in trial NCT05054725?

The interventions under investigation include: Sotorasib (DRUG), RMC-4630 (DRUG).

Who is sponsoring clinical trial NCT05054725?

This trial is sponsored by Revolution Medicines, which has 16 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.