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NCT05046639 · ClinicalTrials.gov registry record · Phase 4
Sciatic Block in Contralateral Limb Phantom and Residual Limb Pain
A Phase 4 study, sponsored by Northwestern University.
- Terminated
- Registry status
- Phase 4
- Development phase
- 1
- Enrollment target
NCT05046639: Clinical Trial Phase 4 study, sponsored by Northwestern University.
NCT05046639 is a Phase 4 study that was terminated before completion, run by Northwestern University. The registered enrollment target is 1 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05046639, a Phase 4 study, was terminated before completion, sponsored by Northwestern University.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 1 participants
- Enrollment target
Study Summary
Participants with chronic, refractory phantom limb pain (PLP) or residual limb pain (RLP) for more than 6 months will be enrolled in this clinical trial. Aim: Define the attributable pain relief and functional improvement in participants with PLP/RLP after contralateral limb sciatic nerve block. Also, contribute to the basic science understanding of the crossed-withdraw reflex by demonstrating a known animal model phenomenon in human participants. Hypothesis: Contralateral limb sciatic nerve anesthetic block with 2% lidocaine provides immediate clinically meaningful pain reduction, defined as the proportion of patients with at least 50% improvement in numeric rating scale (NRS) pain score in PLP/RLP when compared to sham.
Primary Outcome
Proportions of Participants Reporting ≥ 50% Improvement in NRS pain score on a scale of 0 (no pain) to 10 (worst pain imaginable) from baseline at 15 minutes in treatment and sham groups.
Interventions
- DRUG 10 mL 2% lidocaine
- DRUG 10 mL preservative free saline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2021-09-01 |
| Est. Completion | 2023-07-26 |
| Phase | Phase 4 |
Why NCT05046639 stopped before completion
NCT05046639 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which 10 mL 2% lidocaine is the first listed.
NCT05046639 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05046639 about?
NCT05046639 is a clinical study titled "Sciatic Block in Contralateral Limb Phantom and Residual Limb Pain". Participants with chronic, refractory phantom limb pain (PLP) or residual limb pain (RLP) for more than 6 months will be enrolled in this clinical trial. Aim: Define the attributable pain relief and functional improvement in participants with PLP/RLP after contralateral limb sciatic nerve block. Als...
What is the current status of trial NCT05046639?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 1 participants. The study started on 2021-09-01. Estimated completion is 2023-07-26.
What interventions are being tested in trial NCT05046639?
The interventions under investigation include: 10 mL 2% lidocaine (DRUG), 10 mL preservative free saline (DRUG).
Who is sponsoring clinical trial NCT05046639?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05046639's enrollment target sits among peer trials
1 2000th of 2000 the lowest of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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