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NCT05041426 · ClinicalTrials.gov registry record · Phase 2

Letermovir for CMV Prevention After Lung Transplantation

A Phase 2 study, sponsored by Fernanda P Silveira, MD, MS.

Completed
Registry status
Phase 2
Development phase
15
Enrollment target

NCT05041426: Completed Phase 2 study, sponsored by Fernanda P Silveira, MD, MS.

NCT05041426 is a Phase 2 study that has completed, run by Fernanda P Silveira, MD, MS. The registered enrollment target is 15 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05041426, a Phase 2 study, has completed, sponsored by Fernanda P Silveira, MD, MS.

COMPLETED
Registry status
Phase 2
Development phase
15 participants
Enrollment target

Study Summary

This is an interventional, open-label, single center, pilot study with historical controls to test the efficacy of letermovir (LET) for the prevention of CMV infection and disease in adult lung transplant recipients (LTRs) with idiopathic pulmonary fibrosis (IPF).

Primary Outcome

Number of lung transplant recipients with idiopathic pulmonary fibrosis with CMV infection or disease during letermovir prophylaxis.

Interventions

  • DRUG Letermovir
  • DRUG Valganciclovir

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2021-12-06
Est. Completion 2025-03-03
Phase Phase 2
Fernanda P Silveira, MD, MS

2 total trials

What the finished NCT05041426 record still lists

NCT05041426 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (89% lower).

The record links to 0 conditions, and to 2 interventions - of which Letermovir is the first listed.

NCT05041426 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05041426 about?

NCT05041426 is a clinical study titled "Letermovir for CMV Prevention After Lung Transplantation". This is an interventional, open-label, single center, pilot study with historical controls to test the efficacy of letermovir (LET) for the prevention of CMV infection and disease in adult lung transplant recipients (LTRs) with idiopathic pulmonary fibrosis (IPF).

What is the current status of trial NCT05041426?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2021-12-06. Estimated completion is 2025-03-03.

What interventions are being tested in trial NCT05041426?

The interventions under investigation include: Letermovir (DRUG), Valganciclovir (DRUG).

Who is sponsoring clinical trial NCT05041426?

This trial is sponsored by Fernanda P Silveira, MD, MS, which has 2 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05041426's enrollment target sits among peer trials

15 1919th of 2000 higher than 60 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05041426, the US trial registry maintained by the National Library of Medicine. NCT05041426 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.