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NCT05032820 · ClinicalTrials.gov registry record · Phase 2

Upfront Chimeric Antigen Receptor T-Cell to Upgrade Response in Multiple Myeloma

A Phase 2 study, sponsored by Medical College of Wisconsin.

Completed
Registry status
Phase 2
Development phase
40
Enrollment target

NCT05032820 is a Phase 2 study that has completed, run by Medical College of Wisconsin. The registered enrollment target is 40 participants.

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The verdict

NCT05032820, a Phase 2 study, has completed, sponsored by Medical College of Wisconsin.

COMPLETED
Registry status
Phase 2
Development phase
40 participants
Enrollment target

Study Summary

This study is designed as a Phase II, multicenter, single arm trial to assess anti-B Cell Maturation Antigen (BCMA) chimeric antigen receptor (CAR) T-cells (bb2121) to improve post autologous hematopoietic cell transplant (HCT) responses among patients with multiple myeloma (MM).

Interventions

  • DRUG Cyclophosphamide
  • DRUG Fludarabine
  • DRUG Lenalidomide
  • PROCEDURE leukapheresis
  • BIOLOGICAL bb2121

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2022-01-05
Est. Completion 2025-02-20
Phase Phase 2

Sponsor

Medical College of Wisconsin

447 total trials

What the Registry Record Tells You About NCT05032820

The ClinicalTrials.gov registry entry for NCT05032820 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical College of Wisconsin, which has 447 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Cyclophosphamide is the first listed.

NCT05032820 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT05032820 about?

NCT05032820 is a clinical study titled "Upfront Chimeric Antigen Receptor T-Cell to Upgrade Response in Multiple Myeloma". This study is designed as a Phase II, multicenter, single arm trial to assess anti-B Cell Maturation Antigen (BCMA) chimeric antigen receptor (CAR) T-cells (bb2121) to improve post autologous hematopoietic cell transplant (HCT) responses among patients with multiple myeloma (MM).

What is the current status of trial NCT05032820?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2022-01-05. Estimated completion is 2025-02-20.

What interventions are being tested in trial NCT05032820?

The interventions under investigation include: Cyclophosphamide (DRUG), Fludarabine (DRUG), Lenalidomide (DRUG), leukapheresis (PROCEDURE), bb2121 (BIOLOGICAL).

Who is sponsoring clinical trial NCT05032820?

This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.