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NCT05008198 · ClinicalTrials.gov registry record

Assessing an EEG Biomarker of Response to TMS for Major Depression

A clinical trial of Depression, sponsored by VA Office of Research and Development.

Active
Registry status
266
Enrollment target
1
Study location

NCT05008198: Active study of Depression, sponsored by VA Office of Research and Development.

NCT05008198 is a study of Depression that is active but no longer recruiting, run by VA Office of Research and Development. The registered enrollment target is 266 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (66% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05008198, a study of Depression, is active but no longer recruiting, sponsored by VA Office of Research and Development.

ACTIVE NOT RECRUITING
Registry status
266 participants
Enrollment target
1
Study location

Study Summary

Veterans with treatment resistant depression (TRD) have the opportunity to receive transcranial magnetic stimulation (TMS) treatment via the VA's National TMS Clinical Pilot Program. While some see improvement with their depression, others do not. Therefore, it may be beneficial to be able to predict with biomarkers what participants may see improvement with their treatment. Electroencephalography (EEG) is a means to identify such biomarkers. Four hundred Veterans with TRD will be enrolled in this trial to determine whether neuroimaging biomarkers of repetitive transcranial magnetic stimulation (TMS) can be prospectively replicated in a large ecologically valid sample. Participants will have a total of EEG scans at baseline, every 5th treatment session, and at the end of treatment for a total of 7 EEG scans.

Conditions Studied

Interventions

  • OTHER Transcranial Magnetic Stimulation

Study Locations (1)

Vermont

  • White River Junction VA Medical Center, White River Junction, VT - White River Junction

Trial Details

FieldValue
Enrollment Target 266 participants
Start Date 2021-08-19
Est. Completion 2026-09-30

Sponsor

VA Office of Research and Development

1,668 total trials

What the Registry Record Tells You About NCT05008198

The ClinicalTrials.gov registry entry for NCT05008198 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 266 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (66% lower). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Transcranial Magnetic Stimulation is the first listed.

NCT05008198 reports 1 study location spanning 1 distinct geographic area - top geographies include Vermont.

Frequently Asked Questions

What is clinical trial NCT05008198 about?

NCT05008198 is a clinical study titled "Assessing an EEG Biomarker of Response to TMS for Major Depression". Veterans with treatment resistant depression (TRD) have the opportunity to receive transcranial magnetic stimulation (TMS) treatment via the VA's National TMS Clinical Pilot Program. While some see improvement with their depression, others do not. Therefore, it may be beneficial to be able to predic...

What is the current status of trial NCT05008198?

This trial is currently active not recruiting. The enrollment target is 266 participants. The study started on 2021-08-19. Estimated completion is 2026-09-30.

What conditions does trial NCT05008198 study?

This clinical trial studies the following conditions: Depression.

What interventions are being tested in trial NCT05008198?

The interventions under investigation include: Transcranial Magnetic Stimulation (OTHER).

Who is sponsoring clinical trial NCT05008198?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05008198 being conducted?

This trial has 1 study location across Vermont. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.