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NCT05005338 · ClinicalTrials.gov registry record · Phase 1
A Study to Determine the Absolute Bioavailability of BIIB122/DNL151 in Healthy Subjects
A Phase 1 study, sponsored by Biogen.
- Completed
- Registry status
- Phase 1
- Development phase
- 8
- Enrollment target
NCT05005338: Completed Phase 1 study, sponsored by Biogen.
NCT05005338 is a Phase 1 study that has completed, run by Biogen. The registered enrollment target is 8 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05005338, a Phase 1 study, has completed, sponsored by Biogen.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 8 participants
- Enrollment target
Study Summary
This is a single center, non-randomized, open label Phase 1 study to determine the PK and absolute bioavailability of BIIB122 (DNL151) in 2 conditions: following a single, oral dose of BIIB122 (DNL151) and following consecutive days of oral dosing, approximating steady state.
Interventions
- DRUG [14C] BIIB122 ([14C] DNL151)
- DRUG BIIB122 (DNL151)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2021-07-28 |
| Est. Completion | 2021-09-23 |
| Phase | Phase 1 |
What the finished NCT05005338 record still lists
NCT05005338 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 2 interventions - of which [14C] BIIB122 ([14C] DNL151) is the first listed.
NCT05005338 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05005338 about?
NCT05005338 is a clinical study titled "A Study to Determine the Absolute Bioavailability of BIIB122/DNL151 in Healthy Subjects". This is a single center, non-randomized, open label Phase 1 study to determine the PK and absolute bioavailability of BIIB122 (DNL151) in 2 conditions: following a single, oral dose of BIIB122 (DNL151) and following consecutive days of oral dosing, approximating steady state.
What is the current status of trial NCT05005338?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2021-07-28. Estimated completion is 2021-09-23.
What interventions are being tested in trial NCT05005338?
The interventions under investigation include: [14C] BIIB122 ([14C] DNL151) (DRUG), BIIB122 (DNL151) (DRUG).
Who is sponsoring clinical trial NCT05005338?
This trial is sponsored by Biogen, which has 334 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05005338's enrollment target sits among peer trials
8 1959th of 2000 higher than 29 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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