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NCT05004025 · ClinicalTrials.gov registry record · Phase 1
Single Arm Trial of Tumor-Treating Fields in Combination With Nivolumab and Ipilimumab in Metastatic Uveal Melanoma
A Phase 1 study, sponsored by HonorHealth Research Institute.
- Completed
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
NCT05004025: Completed Phase 1 study, sponsored by HonorHealth Research Institute.
NCT05004025 is a Phase 1 study that has completed, run by HonorHealth Research Institute. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05004025, a Phase 1 study, has completed, sponsored by HonorHealth Research Institute.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
Study Summary
Tumor Treating Fields targeted to liver metastases may improve outcomes for patients with metastatic uveal melanoma treated with immune checkpoint inhibitors.
Primary Outcome
evaluate the overall response rate of patients with mUM treated with TTF in combination with nivolumab and ipilimumab.
Interventions
- DRUG Yervoy
- DEVICE Novocure Optune
- DRUG Opdivo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2022-02-28 |
| Est. Completion | 2025-07-23 |
| Phase | Phase 1 |
What the finished NCT05004025 record still lists
NCT05004025 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 3 interventions - of which Yervoy is the first listed.
NCT05004025 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05004025 about?
NCT05004025 is a clinical study titled "Single Arm Trial of Tumor-Treating Fields in Combination With Nivolumab and Ipilimumab in Metastatic Uveal Melanoma". Tumor Treating Fields targeted to liver metastases may improve outcomes for patients with metastatic uveal melanoma treated with immune checkpoint inhibitors.
What is the current status of trial NCT05004025?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2022-02-28. Estimated completion is 2025-07-23.
What interventions are being tested in trial NCT05004025?
The interventions under investigation include: Yervoy (DRUG), Novocure Optune (DEVICE), Opdivo (DRUG).
Who is sponsoring clinical trial NCT05004025?
This trial is sponsored by HonorHealth Research Institute, which has 20 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05004025's enrollment target sits among peer trials
10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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