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NCT05003856 · ClinicalTrials.gov registry record · NA

Radiofrequency Ablation for the Treatment of Benign or Low Risk Thyroid Nodule

A NA study, sponsored by M.D. Anderson Cancer Center.

Terminated
Registry status
NA
Development phase
1
Enrollment target

NCT05003856: Clinical Trial NA study, sponsored by M.D. Anderson Cancer Center.

NCT05003856 is a NA study that was terminated before completion, run by M.D. Anderson Cancer Center. The registered enrollment target is 1 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05003856, a NA study, was terminated before completion, sponsored by M.D. Anderson Cancer Center.

TERMINATED
Registry status
NA
Development phase
1 participants
Enrollment target

Study Summary

This phase IV trial studies the effect of radiofrequency ablation in treating patients with benign or low risk thyroid nodule. Radiofrequency ablation uses a needle to deliver a high-frequency electric current to kill tumor cells by heating them. The goal of this research study is to learn if ultrasound guided radiofrequency ablation can provide the same treatment result as standard surgical removal of the thyroid nodule, small primary thyroid, or thyroid cancers that have come back. Researchers also want to learn if the procedure can be less invasive and perhaps provide a better recovery response than surgery.

Primary Outcome

The change from baseline to follow-up will be evaluated using Wilcoxon signed-rank tests. Additionally, will assess the association between changes in the nodule volume and covariates of interest, including but not excluded to the percentage of volume ablated, the nodule composition at treatment and follow-up, and the amount of energy delivered in Joules.

Interventions

  • OTHER Quality-of-Life Assessment
  • PROCEDURE Radiofrequency Ablation

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2022-08-29
Est. Completion 2025-03-27
Phase NA
M.D. Anderson Cancer Center

2,692 total trials

Why NCT05003856 stopped before completion

NCT05003856 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 2 interventions - of which Quality-of-Life Assessment is the first listed.

NCT05003856 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05003856 about?

NCT05003856 is a clinical study titled "Radiofrequency Ablation for the Treatment of Benign or Low Risk Thyroid Nodule". This phase IV trial studies the effect of radiofrequency ablation in treating patients with benign or low risk thyroid nodule. Radiofrequency ablation uses a needle to deliver a high-frequency electric current to kill tumor cells by heating them. The goal of this research study is to learn if ultras...

What is the current status of trial NCT05003856?

This trial is currently terminated. It is a NA study. The enrollment target is 1 participants. The study started on 2022-08-29. Estimated completion is 2025-03-27.

What interventions are being tested in trial NCT05003856?

The interventions under investigation include: Quality-of-Life Assessment (OTHER), Radiofrequency Ablation (PROCEDURE).

Who is sponsoring clinical trial NCT05003856?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05003856's enrollment target sits among peer trials

1 2001st of 2000 the lowest of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05003856, the US trial registry maintained by the National Library of Medicine. NCT05003856 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.