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NCT04994301 · ClinicalTrials.gov registry record
Evaluation of Lung T1-MRI in Pediatric Cystic Fibrosis Patients
A clinical trial, sponsored by University Hospitals Cleveland Medical Center.
- Completed
- Registry status
- 56
- Enrollment target
NCT04994301: Completed study, sponsored by University Hospitals Cleveland Medical Center.
NCT04994301 is a clinical trial that has completed, run by University Hospitals Cleveland Medical Center. The registered enrollment target is 56 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04994301 has completed, sponsored by University Hospitals Cleveland Medical Center.
- COMPLETED
- Registry status
- 56 participants
- Enrollment target
Study Summary
In this observational study, the investigators evaluate the sensitivity of T1-MRI to identify lung perfusion changes in pediatric patients with CF (age = 6-11) before and after initiating FDA-approved Trikafta therapy. The investigators compare these Lung T1 MRI assessments (% Normal lung perfusion) to currently best-available assessments of lung function in CF patients (i.e., MBW (LCI( and Spirometry (FEV1 % Predicted).
Primary Outcome
Evaluate lung T1-MRI (% Normal Lung Perfusion) to assess lung perfusion changes associated with FDA-approved Trikafta therapy in pediatric cystic fibrosis patients.
Interventions
- DIAGNOSTIC_TEST Lung T1 MRI
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2020-12-15 |
| Est. Completion | 2023-12-15 |
What the finished NCT04994301 record still lists
NCT04994301 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 56 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Lung T1 MRI is the first listed.
NCT04994301 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04994301 about?
NCT04994301 is a clinical study titled "Evaluation of Lung T1-MRI in Pediatric Cystic Fibrosis Patients". In this observational study, the investigators evaluate the sensitivity of T1-MRI to identify lung perfusion changes in pediatric patients with CF (age = 6-11) before and after initiating FDA-approved Trikafta therapy. The investigators compare these Lung T1 MRI assessments (% Normal lung perfusion)...
What is the current status of trial NCT04994301?
This trial is currently completed. The enrollment target is 56 participants. The study started on 2020-12-15. Estimated completion is 2023-12-15.
What interventions are being tested in trial NCT04994301?
The interventions under investigation include: Lung T1 MRI (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04994301?
This trial is sponsored by University Hospitals Cleveland Medical Center, which has 230 total clinical trials registered on ClinicalTrials.gov.
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