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NCT04994301 · ClinicalTrials.gov registry record

Evaluation of Lung T1-MRI in Pediatric Cystic Fibrosis Patients

A clinical trial, sponsored by University Hospitals Cleveland Medical Center.

Completed
Registry status
56
Enrollment target

NCT04994301 is a clinical trial that has completed, run by University Hospitals Cleveland Medical Center. The registered enrollment target is 56 participants.

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The verdict

NCT04994301 has completed, sponsored by University Hospitals Cleveland Medical Center.

COMPLETED
Registry status
56 participants
Enrollment target

Study Summary

In this observational study, the investigators evaluate the sensitivity of T1-MRI to identify lung perfusion changes in pediatric patients with CF (age = 6-11) before and after initiating FDA-approved Trikafta therapy. The investigators compare these Lung T1 MRI assessments (% Normal lung perfusion) to currently best-available assessments of lung function in CF patients (i.e., MBW (LCI( and Spirometry (FEV1 % Predicted).

Interventions

  • DIAGNOSTIC_TEST Lung T1 MRI

Trial Details

FieldValue
Enrollment Target 56 participants
Start Date 2020-12-15
Est. Completion 2023-12-15

What the Registry Record Tells You About NCT04994301

The ClinicalTrials.gov registry entry for NCT04994301 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 56 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University Hospitals Cleveland Medical Center, which has 230 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Lung T1 MRI is the first listed.

NCT04994301 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04994301 about?

NCT04994301 is a clinical study titled "Evaluation of Lung T1-MRI in Pediatric Cystic Fibrosis Patients". In this observational study, the investigators evaluate the sensitivity of T1-MRI to identify lung perfusion changes in pediatric patients with CF (age = 6-11) before and after initiating FDA-approved Trikafta therapy. The investigators compare these Lung T1 MRI assessments (% Normal lung perfusion)...

What is the current status of trial NCT04994301?

This trial is currently completed. The enrollment target is 56 participants. The study started on 2020-12-15. Estimated completion is 2023-12-15.

What interventions are being tested in trial NCT04994301?

The interventions under investigation include: Lung T1 MRI (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT04994301?

This trial is sponsored by University Hospitals Cleveland Medical Center, which has 230 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.