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NCT04993742 · ClinicalTrials.gov registry record · NA
Effects of Pregnancy-Specific Anxiety on Placental Inflammatory and Oxidative Stress Response and Birth Outcomes
A NA study of Prenatal Stress and Placental Dysfunction, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.
- Active
- Registry status
- NA
- Development phase
- 150
- Enrollment target
- 1
- Study location
NCT04993742: Active NA study of Prenatal Stress and Placental Dysfunction, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.
NCT04993742 is a NA study of Prenatal Stress and Placental Dysfunction that is active but no longer recruiting, run by Henry M. Jackson Foundation for the Advancement of Military Medicine. The registered enrollment target is 150 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04993742, a NA study of Prenatal Stress and Placental Dysfunction, is active but no longer recruiting, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
Explore the associations of prenatal maternal anxiety to placental histologic findings, and the pro-inflammatory, anti-inflammatory, and immunoregulatory cells found in the placenta and determine the effect of maternal anxiety on the association between placental molecular changes on pregnancy and birth and infant outcomes.
Primary Outcome
Correlate % of participants with increased measures of anxiety and depression will be associated with changes in Th1, Th2, and Th17 responses as well as an increase in hormonal and oxidative stress biomarkers indicative of a proinflammatory and physiological stressed state.
Conditions Studied
Interventions
- BEHAVIORAL MOMS Intervention
Study Locations (1)
Texas
- Joint Base San Antonio - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2019-11-26 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What the registry record for NCT04993742 still lists
NCT04993742 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower).
The record links to 2 conditions, with Prenatal Stress appearing as the primary indexed condition, and to 1 intervention - of which MOMS Intervention is the first listed.
NCT04993742 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT04993742 about?
NCT04993742 is a clinical study titled "Effects of Pregnancy-Specific Anxiety on Placental Inflammatory and Oxidative Stress Response and Birth Outcomes". Explore the associations of prenatal maternal anxiety to placental histologic findings, and the pro-inflammatory, anti-inflammatory, and immunoregulatory cells found in the placenta and determine the effect of maternal anxiety on the association between placental molecular changes on pregnancy and b...
What is the current status of trial NCT04993742?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 150 participants. The study started on 2019-11-26. Estimated completion is 2026-12-31.
What conditions does trial NCT04993742 study?
This clinical trial studies the following conditions: Prenatal Stress, Placental Dysfunction.
What interventions are being tested in trial NCT04993742?
The interventions under investigation include: MOMS Intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT04993742?
This trial is sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine, which has 60 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04993742 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04993742's enrollment target sits among peer trials
150 661st of 2000 higher than 1,299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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