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NCT04990804 · ClinicalTrials.gov registry record · Phase 4
Opioid Free vs. Standard Perioperative Pain Regimen for Anterior Cervical Discectomy and Fusion (ACDF) Surgery
A Phase 4 study, sponsored by Vanderbilt University Medical Center.
- Terminated
- Registry status
- Phase 4
- Development phase
- 8
- Enrollment target
NCT04990804: Clinical Trial Phase 4 study, sponsored by Vanderbilt University Medical Center.
NCT04990804 is a Phase 4 study that was terminated before completion, run by Vanderbilt University Medical Center. The registered enrollment target is 8 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04990804, a Phase 4 study, was terminated before completion, sponsored by Vanderbilt University Medical Center.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 8 participants
- Enrollment target
Study Summary
Patients undergoing 1-3 level Anterior Cervical Discectomy and Fusion (ACDF) at the levels between C2 and T1 will be enrolled into this randomized prospective study. All patients enrolled in this study will undergo a trial of non-surgical treatment prior to the recommendation for surgery. After enrollment, patients will be randomized utilizing a block randomization strategy to one of two treatment groups - a standard opioid-containing postoperative pain regimen versus a non-opioid postoperative pain regimen. Postoperative outcomes will be assessed.
Primary Outcome
Opioid prescription for \> or = 45 days in 90 day window (9-12 months postoperatively)
Interventions
- DRUG Opioid Analgesic
- DRUG Opioid-Free Postoperative Pain Regimen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2021-08-01 |
| Est. Completion | 2022-02-01 |
| Phase | Phase 4 |
Why NCT04990804 stopped before completion
NCT04990804 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Opioid Analgesic is the first listed.
NCT04990804 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04990804 about?
NCT04990804 is a clinical study titled "Opioid Free vs. Standard Perioperative Pain Regimen for Anterior Cervical Discectomy and Fusion (ACDF) Surgery". Patients undergoing 1-3 level Anterior Cervical Discectomy and Fusion (ACDF) at the levels between C2 and T1 will be enrolled into this randomized prospective study. All patients enrolled in this study will undergo a trial of non-surgical treatment prior to the recommendation for surgery. After enro...
What is the current status of trial NCT04990804?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 8 participants. The study started on 2021-08-01. Estimated completion is 2022-02-01.
What interventions are being tested in trial NCT04990804?
The interventions under investigation include: Opioid Analgesic (DRUG), Opioid-Free Postoperative Pain Regimen (DRUG).
Who is sponsoring clinical trial NCT04990804?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04990804's enrollment target sits among peer trials
8 1972nd of 2000 higher than 20 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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