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NCT04989920 · ClinicalTrials.gov registry record · NA
Brain and Behavior Correlates of Arm Rehabilitation
A NA study, sponsored by University of Southern California.
- Completed
- Registry status
- NA
- Development phase
- 23
- Enrollment target
NCT04989920: Completed NA study, sponsored by University of Southern California.
NCT04989920 is a NA study that has completed, run by University of Southern California. The registered enrollment target is 23 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04989920, a NA study, has completed, sponsored by University of Southern California.
- COMPLETED
- Registry status
- NA
- Development phase
- 23 participants
- Enrollment target
Study Summary
This project is designed to use three-dimensional movement analysis and magnetic resonance (fMRI) neuroimaging techniques to examine the brain activity and motor behavior changes associated with constraint-induced (CI) therapy for patients with sub-acute stroke (3-9 months post-stroke).Participants are evaluated at 5 time points-1-mo (pre \& post), 6-mo (pre \& post), and 12-mo. Each person is randomized to receive CI therapy either between pre- and post-evaluations or after the 6-mo pre-evaluation. We will determine the effects of CI therapy on 1) reaching and grasping actions using behavioral kinematics and 2) the sensorimotor network through fMRI scans with goal-directed aiming and grasping tasks. We will also determine the relationship between lesion size and location using 3-D volumetric MRI scans and behavioral outcomes as a consequence of CI therapy.
Primary Outcome
The primary outcome measure for BCAR and to which we will correlate our brain and behavior measures are the Wolf motor function test (Wolf et al., 2001) and the Motor Activity Log (a semi-structured interview) of arm use for 30 ADL in the home. These measures of arm use capture arm function in the laboratory and in the real world and have acceptable psychometric properties.
Interventions
- BEHAVIORAL Experimental group: CIMT group (Constraint-Induced Movement Therapy)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2003-04-28 |
| Est. Completion | 2011-07-15 |
| Phase | NA |
What the finished NCT04989920 record still lists
NCT04989920 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Experimental group: CIMT group (Constraint-Induced Movement Therapy) is the first listed.
NCT04989920 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04989920 about?
NCT04989920 is a clinical study titled "Brain and Behavior Correlates of Arm Rehabilitation". This project is designed to use three-dimensional movement analysis and magnetic resonance (fMRI) neuroimaging techniques to examine the brain activity and motor behavior changes associated with constraint-induced (CI) therapy for patients with sub-acute stroke (3-9 months post-stroke).Participants ...
What is the current status of trial NCT04989920?
This trial is currently completed. It is a NA study. The enrollment target is 23 participants. The study started on 2003-04-28. Estimated completion is 2011-07-15.
What interventions are being tested in trial NCT04989920?
The interventions under investigation include: Experimental group: CIMT group (Constraint-Induced Movement Therapy) (BEHAVIORAL).
Who is sponsoring clinical trial NCT04989920?
This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04989920's enrollment target sits among peer trials
23 1755th of 2000 higher than 245 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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