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NCT04986956 · ClinicalTrials.gov registry record · NA

Whole Coffee Cherry Study

A NA study, sponsored by Auburn University.

Completed
Registry status
NA
Development phase
323
Enrollment target

NCT04986956 is a NA study that has completed, run by Auburn University. The registered enrollment target is 323 participants.

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The verdict

NCT04986956, a NA study, has completed, sponsored by Auburn University.

COMPLETED
Registry status
NA
Development phase
323 participants
Enrollment target

Study Summary

There has been increasing interest in natural dietary supplements that may support healthy cognition. Recent studies have demonstrated promising effects of bioactive phytochemicals (e.g., polyphenols) on cardiovascular and endocrine health outcomes. As such, an increasingly intriguing line of inquiry is whether materials high in these compounds may also have effects on psychological measures. Preliminary evidence suggests that polyphenols may improve cognition, for example, particularly in aging populations. Whole coffee cherry extract (WCCE; otherwise known as the generally-recognized-as-safe (GRAS) supplement Neurofactor(TM)), is a proprietary, safe, powdered extract of whole coffee cherries from coffea arabica with high levels of polyphenols and substantially low (\<2%; \<4mg) levels of caffeine. WCCE has been previously associated with increased serum concentrations of both circulating and exosomal brain derived neurotrophic factor (BDNF), in addition to increased alertness and decreased fatigue. However, few well-powered and well-designed studies have been conducted despite the mounting preliminary evidence. Here, the investigators propose a study to examine the long-term effects of a 200mg dose of WCCE on measures of cognition.

Interventions

  • DIETARY_SUPPLEMENT Placebo
  • DIETARY_SUPPLEMENT Whole coffee cherry extract

Trial Details

FieldValue
Enrollment Target 323 participants
Start Date 2022-02-01
Est. Completion 2024-01-29
Phase NA

Sponsor

Auburn University

54 total trials

What the Registry Record Tells You About NCT04986956

The ClinicalTrials.gov registry entry for NCT04986956 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 323 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Auburn University, which has 54 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04986956 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04986956 about?

NCT04986956 is a clinical study titled "Whole Coffee Cherry Study". There has been increasing interest in natural dietary supplements that may support healthy cognition. Recent studies have demonstrated promising effects of bioactive phytochemicals (e.g., polyphenols) on cardiovascular and endocrine health outcomes. As such, an increasingly intriguing line of inquir...

What is the current status of trial NCT04986956?

This trial is currently completed. It is a NA study. The enrollment target is 323 participants. The study started on 2022-02-01. Estimated completion is 2024-01-29.

What interventions are being tested in trial NCT04986956?

The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), Whole coffee cherry extract (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT04986956?

This trial is sponsored by Auburn University, which has 54 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.