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NCT04984278 · ClinicalTrials.gov registry record · Phase 3

Evaluation of the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis

A Phase 3 study, sponsored by Jazz Pharmaceuticals.

Terminated
Registry status
Phase 3
Development phase
56
Enrollment target

NCT04984278 is a Phase 3 study that was terminated before completion, run by Jazz Pharmaceuticals. The registered enrollment target is 56 participants.

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The verdict

NCT04984278, a Phase 3 study, was terminated before completion, sponsored by Jazz Pharmaceuticals.

TERMINATED
Registry status
Phase 3
Development phase
56 participants
Enrollment target

Study Summary

This study will be conducted to evaluate the effect of multiple doses of nabiximols compared with placebo on a clinical measure of velocity-dependent muscle tone in the lower limbs (Lower Limb Muscle Tone-6 \[LLMT-6\]) in participants with multiple sclerosis (MS). LLMT-6 is defined as the average of the 6 individual Modified Ashworth Scale (MAS)-transformed scores of knee flexors, knee extensors, and plantar flexors on both sides of the body.

Interventions

  • DRUG Placebo
  • DRUG Nabiximols

Trial Details

FieldValue
Enrollment Target 56 participants
Start Date 2021-08-16
Est. Completion 2022-11-11
Phase Phase 3

Sponsor

Jazz Pharmaceuticals

128 total trials

What the Registry Record Tells You About NCT04984278

The ClinicalTrials.gov registry entry for NCT04984278 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 56 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jazz Pharmaceuticals, which has 128 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT04984278 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04984278 about?

NCT04984278 is a clinical study titled "Evaluation of the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis". This study will be conducted to evaluate the effect of multiple doses of nabiximols compared with placebo on a clinical measure of velocity-dependent muscle tone in the lower limbs (Lower Limb Muscle Tone-6 \[LLMT-6\]) in participants with multiple sclerosis (MS). LLMT-6 is defined as the average of...

What is the current status of trial NCT04984278?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 56 participants. The study started on 2021-08-16. Estimated completion is 2022-11-11.

What interventions are being tested in trial NCT04984278?

The interventions under investigation include: Placebo (DRUG), Nabiximols (DRUG).

Who is sponsoring clinical trial NCT04984278?

This trial is sponsored by Jazz Pharmaceuticals, which has 128 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.