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NCT04981704 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Effect of Multiple Doses of Itraconazole, Phenytoin, and Paroxetine on the Single-Dose Pharmacokinetics of Poziotinib in Healthy Adult Participants
A Phase 1 study, sponsored by Spectrum Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 74
- Enrollment target
NCT04981704: Completed Phase 1 study, sponsored by Spectrum Pharmaceuticals.
NCT04981704 is a Phase 1 study that has completed, run by Spectrum Pharmaceuticals. The registered enrollment target is 74 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (23% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04981704, a Phase 1 study, has completed, sponsored by Spectrum Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 74 participants
- Enrollment target
Study Summary
The purpose of the study is to evaluate the effect of multiple-doses of itraconazole, phenytoin and paroxetine on the single-dose pharmacokinetics (PK) of poziotinib in healthy adult participants.
Interventions
- DRUG Itraconazole
- DRUG Paroxetine
- DRUG Phenytoin
- DRUG Poziotinib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 74 participants |
| Start Date | 2021-04-08 |
| Est. Completion | 2021-08-17 |
| Phase | Phase 1 |
What the finished NCT04981704 record still lists
NCT04981704 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 74 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (23% higher).
The record links to 0 conditions, and to 4 interventions - of which Itraconazole is the first listed.
NCT04981704 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04981704 about?
NCT04981704 is a clinical study titled "A Study to Evaluate the Effect of Multiple Doses of Itraconazole, Phenytoin, and Paroxetine on the Single-Dose Pharmacokinetics of Poziotinib in Healthy Adult Participants". The purpose of the study is to evaluate the effect of multiple-doses of itraconazole, phenytoin and paroxetine on the single-dose pharmacokinetics (PK) of poziotinib in healthy adult participants.
What is the current status of trial NCT04981704?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 74 participants. The study started on 2021-04-08. Estimated completion is 2021-08-17.
What interventions are being tested in trial NCT04981704?
The interventions under investigation include: Itraconazole (DRUG), Paroxetine (DRUG), Phenytoin (DRUG), Poziotinib (DRUG).
Who is sponsoring clinical trial NCT04981704?
This trial is sponsored by Spectrum Pharmaceuticals, which has 52 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04981704's enrollment target sits among peer trials
74 725th of 2000 higher than 1,269 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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