Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04980456 · ClinicalTrials.gov registry record · NA
Clinical Assessment of Two Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lenses
A NA study, sponsored by Alcon Research.
- Completed
- Registry status
- NA
- Development phase
- 257
- Enrollment target
NCT04980456: Completed NA study, sponsored by Alcon Research.
NCT04980456 is a NA study that has completed, run by Alcon Research. The registered enrollment target is 257 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04980456, a NA study, has completed, sponsored by Alcon Research.
- COMPLETED
- Registry status
- NA
- Development phase
- 257 participants
- Enrollment target
Study Summary
The purpose of this study is to compare the clinical performance of TOTAL30 contact lenses with Biofinity contact lenses over 30 days of daily wear.
Primary Outcome
Distance visual acuity (VA) was assessed with study lenses in place. VA was collected for each eye separately using logarithmic of the Minimum Angle of Resolution (logMAR) charts. A logMAR acuity of 0.0 corresponds to 20/20 Snellen acuity (normal visual acuity), with a negative value denoting better than 20/20 visual acuity.
Interventions
- DEVICE Comfilcon A contact lenses
- DEVICE Lehfilcon A contact lenses
- DEVICE CLEAR CARE
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 257 participants |
| Start Date | 2021-08-05 |
| Est. Completion | 2021-11-20 |
| Phase | NA |
What the finished NCT04980456 record still lists
NCT04980456 is an interventional study that assigns participants to a tested intervention. The registered 257 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower).
The record links to 0 conditions, and to 3 interventions - of which Comfilcon A contact lenses is the first listed.
NCT04980456 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04980456 about?
NCT04980456 is a clinical study titled "Clinical Assessment of Two Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lenses". The purpose of this study is to compare the clinical performance of TOTAL30 contact lenses with Biofinity contact lenses over 30 days of daily wear.
What is the current status of trial NCT04980456?
This trial is currently completed. It is a NA study. The enrollment target is 257 participants. The study started on 2021-08-05. Estimated completion is 2021-11-20.
What interventions are being tested in trial NCT04980456?
The interventions under investigation include: Comfilcon A contact lenses (DEVICE), Lehfilcon A contact lenses (DEVICE), CLEAR CARE (DEVICE).
Who is sponsoring clinical trial NCT04980456?
This trial is sponsored by Alcon Research, which has 275 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04980456's enrollment target sits among peer trials
257 403rd of 2000 higher than 1,597 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03618550 · 257 participants · Phase 2
Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin Lymphoma
- NCT04674267 · 257 participants · NA
Resilience and Equity in Aging, Cancer, and Health (REACH)
- NCT06099288 · 257 participants · NA
Strong Families Start at Home/Familias Fuertes Comienzan en Casa
- NCT06207084 · 257 participants · NA
The Fit With Us Study
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI