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NCT04973007 · ClinicalTrials.gov registry record · Phase 4

Comparison of Contrast Agents in Liver Magnetic Resonance (MR) for the Detection of Hepatic Metastases

A Phase 4 study, sponsored by University of Colorado, Denver.

Terminated
Registry status
Phase 4
Development phase
10
Enrollment target

NCT04973007: Clinical Trial Phase 4 study, sponsored by University of Colorado, Denver.

NCT04973007 is a Phase 4 study that was terminated before completion, run by University of Colorado, Denver. The registered enrollment target is 10 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04973007, a Phase 4 study, was terminated before completion, sponsored by University of Colorado, Denver.

TERMINATED
Registry status
Phase 4
Development phase
10 participants
Enrollment target

Study Summary

If an abbreviated hepatobiliary phase (HBP) protocol liver MR with gadobenate dimeglumine is shown clinically comparable to standard of care liver MR with gadoxetate disodium for detecting hepatic metastasis from colorectal cancer, its use will save time, cost, and patients' effort.

Primary Outcome

The primary performance diagnostic will be sensitivity, similar to the recently published retrospective study by Canellas et al. (2019). In addition to other diagnostic performance metrics of interest (e.g., specificity, AUROC), lesions will be analyzed descriptively in terms of number of metastases detected and lesion size.

Interventions

  • DRUG Gadoxetate disodium
  • DRUG Gadobenate dimeglumine

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2021-06-22
Est. Completion 2025-05-08
Phase Phase 4
University of Colorado, Denver

1,283 total trials

Why NCT04973007 stopped before completion

NCT04973007 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 2 interventions - of which Gadoxetate disodium is the first listed.

NCT04973007 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04973007 about?

NCT04973007 is a clinical study titled "Comparison of Contrast Agents in Liver Magnetic Resonance (MR) for the Detection of Hepatic Metastases". If an abbreviated hepatobiliary phase (HBP) protocol liver MR with gadobenate dimeglumine is shown clinically comparable to standard of care liver MR with gadoxetate disodium for detecting hepatic metastasis from colorectal cancer, its use will save time, cost, and patients' effort.

What is the current status of trial NCT04973007?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 10 participants. The study started on 2021-06-22. Estimated completion is 2025-05-08.

What interventions are being tested in trial NCT04973007?

The interventions under investigation include: Gadoxetate disodium (DRUG), Gadobenate dimeglumine (DRUG).

Who is sponsoring clinical trial NCT04973007?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT04973007's enrollment target sits among peer trials

10 1940th of 2000 higher than 33 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04973007, the US trial registry maintained by the National Library of Medicine. NCT04973007 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.