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NCT04971681 · ClinicalTrials.gov registry record · NA
Frontal-Striatal Reward Circuit Neuromodulation and Alcohol Self-Administration
A NA study, sponsored by Indiana University.
- Terminated
- Registry status
- NA
- Development phase
- 9
- Enrollment target
NCT04971681: Clinical Trial NA study, sponsored by Indiana University.
NCT04971681 is a NA study that was terminated before completion, run by Indiana University. The registered enrollment target is 9 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04971681, a NA study, was terminated before completion, sponsored by Indiana University.
- TERMINATED
- Registry status
- NA
- Development phase
- 9 participants
- Enrollment target
Study Summary
This will be a single site randomized, 2-session, within-subject cross-over design pilot study. 20 enrolled (of 30 consented) subjects reporting varying levels of binge and high intensity drinking, defined as at least 2 episodes of drinking 4 (for women) or 5 (for men) drinks on an occasion over the last 5 weeks, (unless determined by PI that drinking history meets study objectives), will be enrolled. Subjects will be randomized to undergo one session of repetitive transcranial magnetic stimulation (rTMS) or sham immediately followed by the investigators rate control intravenous (IV) alcohol self-administration (ASA) paradigm. Subjects will then return 7-14 days later and undergo the same sequence of events with the opposite intervention (i.e. rTMS or sham) from session 1.
Primary Outcome
The amount of time subjects take to self-administer enough alcohol to raise their breath alcohol concentration (BrAC) to 80 mg/dL
Interventions
- DEVICE Sham
- DEVICE Low frequency repetitive transcranial magnetic stimulation (rTMS)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2021-10-08 |
| Est. Completion | 2022-06-02 |
| Phase | NA |
Why NCT04971681 stopped before completion
NCT04971681 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Sham is the first listed.
NCT04971681 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04971681 about?
NCT04971681 is a clinical study titled "Frontal-Striatal Reward Circuit Neuromodulation and Alcohol Self-Administration". This will be a single site randomized, 2-session, within-subject cross-over design pilot study. 20 enrolled (of 30 consented) subjects reporting varying levels of binge and high intensity drinking, defined as at least 2 episodes of drinking 4 (for women) or 5 (for men) drinks on an occasion over the...
What is the current status of trial NCT04971681?
This trial is currently terminated. It is a NA study. The enrollment target is 9 participants. The study started on 2021-10-08. Estimated completion is 2022-06-02.
What interventions are being tested in trial NCT04971681?
The interventions under investigation include: Sham (DEVICE), Low frequency repetitive transcranial magnetic stimulation (rTMS) (DEVICE).
Who is sponsoring clinical trial NCT04971681?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04971681's enrollment target sits among peer trials
9 1975th of 2000 higher than 25 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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